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Referencia número: HY-184595

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(6-OH)-SBP-0636457

(6-OH)-SBP-0636457 is an E3 ubiquitin ligase ligand. (6-OH)-SBP-0636457 can be used to synthesize PROTAC Bcl-xL degrader-1 (HY-131188).

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No. CAS: 3037312-75-4
Fòrmula: C₂₅H₃₆N₄O₅
Peso molecular:472.58

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

(6-OH)-SBP-0636457 Chemical Structure

No. CAS: 3037312-75-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

(6-OH)-SBP-0636457 is an E3 ubiquitin ligase ligand. (6-OH)-SBP-0636457 can be used to synthesize PROTAC Bcl-xL degrader-1 (HY-131188)^[1].

IC₅₀ & Target

IAP

Ver todos los productos específicos de isoformas Ligands for E3 Ligase :

In Vitro

E3 ligases catalyze the transfer of ubiquitin to target proteins and determine protein specificity.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 3037312-75-4
Peso molecular 472.58
Fòrmula C₂₅H₃₆N₄O₅
SMILES

OC1=CC2=C(C=C1)[C@H](NC([C@@H]3C(C)(C[C@@]([H])(N3C4=O)OCC[C@@H]4NC([C@@H](NC)C)=O)C)=O)CCC2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Zhang X, et al.. Discovery of IAP-recruiting BCL-X PROTACs as potent degraders across multiple cancer cell lines. European journal of medicinal chemistry. 2020 Aug 01;199:112397. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(6-OH)-SBP-0636457

Ver todos los productos específicos de isoformas Ligands for E3 Ligase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

(6-OH)-SBP-0636457 Related Classifications

HY-184595 Related Classifications