2. PROTAC
  3. PROTAC Linkers
  4. 8-Bromooctanoic acid

8-Bromooctanoic acid is a PROTAC linker, and can be used for synthesis of PROTAC CYP1B1 degrader-2 (HY-158429).

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8-Bromooctanoic acid

8-Bromooctanoic acid Chemische Struktur

CAS. Nr. : 17696-11-6

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8-Bromooctanoic acid Related Antibodies

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Beschreibung

8-Bromooctanoic acid is a PROTAC linker, and can be used for synthesis of PROTAC CYP1B1 degrader-2 (HY-158429)[1].

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

8-Bromooctanoic acid Related Antibodies
Molekulargewicht

223.11

Formel

C8H15BrO2
CAS. Nr.
Appearance

<35°C Solid,>37°C Liquid

Color

Colorless to off-white

SMILES

O=C(O)CCCCCCCBr
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reinheit & Dokumentation

Purity: 99.89%

SDS (476 KB)

COA (240 KB) HNMR (143 KB) MS (156 KB) GC (178 KB)

Handling Instructions (2659 KB)
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8-Bromooctanoic acid Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

8-Bromooctanoic acid17696-11-6PROTAC LinkersInhibitorinhibitorinhibit

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8-Bromooctanoic acid
Art. -Nr.:
HY-W007700
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SAFETY DATA SHEET (SDS)

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