8alpha-(2-Methylacryloyloxy)-1-O-methylhirsutinolide 13-O-acetate
8alpha-(2-Methylacryloyloxy)-1-O-methylhirsutinolide 13-O-acetate is a Sesquiterpenoids product that can be isolated from the herbs of Vernonia cinerea..
For research use only. We do not sell to patients.
- CAS No.: 883872-71-7
- Formula: C22H28O8
- Molecular Weight:420.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
13.6 μM
Compound: 6
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Inhibition of TNFalpha-induced NF-kappaB activity expressed in human HEK 293 cells after 6 hrs by luciferase reporter gene assay
Inhibition of TNFalpha-induced NF-kappaB activity expressed in human HEK 293 cells after 6 hrs by luciferase reporter gene assay
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[PMID: 22850207] |
| RAW264.7 | IC50 |
1.5 μM
Compound: 6
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Antiinflammatory activity against LPS-induced NO production in mouse RAW264.7 cells assessed as reduction in nitrite level preincubated for 15 mins prior to LPS treatment by Griess method
Antiinflammatory activity against LPS-induced NO production in mouse RAW264.7 cells assessed as reduction in nitrite level preincubated for 15 mins prior to LPS treatment by Griess method
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[PMID: 22850207] |
Chemical Information
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CAS No. 883872-71-7
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Molecular Weight 420.45
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Formula C22H28O8
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SMILES
CC(C(O[C@@H]1C(/C(O2)=C\[C@@]3(O[C@]([C@@H](C1)C)(CC3)OC)C)=C(COC(C)=O)C2=O)=O)=C
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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