1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Dehydroascorbic acid 

Cat. No.: HY-110281
Handling Instructions

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

For research use only. We do not sell to patients.

Dehydroascorbic acid Chemical Structure

Dehydroascorbic acid Chemical Structure

CAS No. : 490-83-5

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7435 mL 28.7175 mL 57.4350 mL
5 mM 1.1487 mL 5.7435 mL 11.4870 mL
10 mM 0.5743 mL 2.8717 mL 5.7435 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

174.11

Formula

C₆H₆O₆

CAS No.

490-83-5

SMILES

OC[[email protected]@H]([[email protected]](O1)([H])C(C(C1=O)=O)=O)O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Dehydroascorbic acid
Cat. No.:
HY-110281
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Dehydroascorbic acid

Cat. No.: HY-110281