490-83-5
Chemical Structure
Dehydroascorbic acid
- CAS No.: 490-83-5
- Formula:C6H6O6
- Molecular Weight:174.11
IUPAC Name: (R)-5-((S)-1,2-dihydroxyethyl)furan-2,3,4(5H)-trione
InChIKey: SBJKKFFYIZUCET-JLAZNSOCSA-N
SMILES: OC[C@H](O)[C@]([H])(C(C1=O)=O)OC1=O
Biological Activity: Dehydroascorbic acid is an oxidized form of vitamin C that can cross the blood-brain barrier (BBB). Dehydroascorbic acid clears cytotoxic reactive oxygen species (ROS) produced after ischemic stroke by converting to ascorbic acid (AA), thereby reducing neuronal and glial cell damage and stabilizing cerebral microvascular NO signaling to maintain perfusion in the ischemic area. Dehydroascorbic acid can be used in research on ischemic stroke[1][2].
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Dehydroascorbic acid | 99.94% | Dehydroascorbic acid is an oxidized form of vitamin C that can cross the blood-brain barrier (BBB). Dehydroascorbic acid clears cytotoxic reactive oxygen species (ROS) produced after ischemic stroke by converting to ascorbic acid (AA), thereby reducing neuronal and glial cell damage and stabilizing cerebral microvascular NO signaling to maintain perfusion in the ischemic area. Dehydroascorbic acid can be used in research on ischemic stroke. | ||||||||||||||||||||
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Dehydroascorbic acid (Standard) | 99.83% | Dehydroascorbic acid (Standard) is the analytical standard of Dehydroascorbic acid. This product is intended for research and analytical applications. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. | ||||||||||||||||||||
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- [1]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potentcerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4. [Content Brief]
- [2]. Huang J, et al. Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11720-4. [Content Brief]
