Siremadlin (R Enantiomer)
Based on 1 Customer Validation
Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.12%
- CAS No.: 1448867-42-2
- Formula: C26H24Cl2N6O4
- Molecular Weight:555.41
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 1448867-42-2
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Appearance Solid
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Molecular Weight 555.41
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Formula C26H24Cl2N6O4
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Color White to off-white
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SMILES
O=C1N(C2=CC(Cl)=CN(C)C2=O)[C@H](C3=CC=C(Cl)C=C3)C4=C1N=C(C5=CN=C(OC)N=C5OC)N4C(C)C
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Synonyms
NVP-HDM201 (R Enantiomer); HDM201 (R Enantiomer)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : ≥ 56.75 mg/mL (102.18 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (247 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8005 mL | 9.0024 mL | 18.0047 mL | 45.0118 mL |
| 5 mM | 0.3601 mL | 1.8005 mL | 3.6009 mL | 9.0024 mL | |
| 10 mM | 0.1800 mL | 0.9002 mL | 1.8005 mL | 4.5012 mL | |
| 15 mM | 0.1200 mL | 0.6002 mL | 1.2003 mL | 3.0008 mL | |
| 20 mM | 0.0900 mL | 0.4501 mL | 0.9002 mL | 2.2506 mL | |
| 25 mM | 0.0720 mL | 0.3601 mL | 0.7202 mL | 1.8005 mL | |
| 30 mM | 0.0600 mL | 0.3001 mL | 0.6002 mL | 1.5004 mL | |
| 40 mM | 0.0450 mL | 0.2251 mL | 0.4501 mL | 1.1253 mL | |
| 50 mM | 0.0360 mL | 0.1800 mL | 0.3601 mL | 0.9002 mL | |
| 60 mM | 0.0300 mL | 0.1500 mL | 0.3001 mL | 0.7502 mL | |
| 80 mM | 0.0225 mL | 0.1125 mL | 0.2251 mL | 0.5626 mL | |
| 100 mM | 0.0180 mL | 0.0900 mL | 0.1800 mL | 0.4501 mL |
Siremadlin (R Enantiomer) Related Classifications
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