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Siremadlin R Enantiomer (Synonyms: NVP-HDM201 R Enantiomer; HDM201 R Enantiomer)

Cat. No.: HY-18658A Purity: 99.19% ee.: 99.85%
Handling Instructions

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor currently under phase I clinical trial.

For research use only. We do not sell to patients.

Siremadlin R Enantiomer Chemical Structure

Siremadlin R Enantiomer Chemical Structure

CAS No. : 1448867-42-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 538 In-stock
Estimated Time of Arrival: December 31
1 mg USD 220 In-stock
Estimated Time of Arrival: December 31
5 mg USD 440 In-stock
Estimated Time of Arrival: December 31
10 mg USD 660 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1950 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Other Forms of Siremadlin R Enantiomer:

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Description

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor currently under phase I clinical trial.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 56.75 mg/mL (102.18 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8005 mL 9.0024 mL 18.0047 mL
5 mM 0.3601 mL 1.8005 mL 3.6009 mL
10 mM 0.1800 mL 0.9002 mL 1.8005 mL
*Please refer to the solubility information to select the appropriate solvent.
Molecular Weight

555.41

Formula

C₂₆H₂₄Cl₂N₆O₄

CAS No.

1448867-42-2

SMILES

O=C1N(C2=CC(Cl)=CN(C)C2=O)[[email protected]](C3=CC=C(Cl)C=C3)C4=C1N=C(C5=CN=C(OC)N=C5OC)N4C(C)C

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.19% ee.: 99.85%

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Siremadlin R Enantiomer
Cat. No.:
HY-18658A
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Siremadlin R Enantiomer

Cat. No.: HY-18658A