Siremadlin (R Enantiomer) (Synonyms: NVP-HDM201 (R Enantiomer); HDM201 (R Enantiomer))

Cat. No.: HY-18658A Purity: 99.12%: FAQs
Data Sheet SDS COA Handling Instructions

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

For research use only. We do not sell to patients.

Siremadlin (R Enantiomer) Chemical Structure

CAS No. : 1448867-42-2

Size	Price	Stock	Quantity
Solution
10 mM * 1 mL in DMSO	USD 484	In-stock	Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL ready for reconstitution	USD 484	In-stock	Estimated Time of Arrival: December 31
Solid
1 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 440	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 660	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 1950	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Siremadlin (R Enantiomer):

Siremadlin In-stock

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Description

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

Molecular Weight

555.41

Appearance

Solid

Formula

C₂₆H₂₄Cl₂N₆O₄

CAS No.

1448867-42-2

SMILES

O=C1N(C2=CC(Cl)=CN(C)C2=O)[[email protected]](C3=CC=C(Cl)C=C3)C4=C1N=C(C5=CN=C(OC)N=C5OC)N4C(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 56.75 mg/mL (102.18 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.8005 mL	9.0024 mL	18.0047 mL
5 mM	0.3601 mL	1.8005 mL	3.6009 mL
10 mM	0.1800 mL	0.9002 mL	1.8005 mL

*Please refer to the solubility information to select the appropriate solvent.

Purity & Documentation

Purity: 99.19%

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Data Sheet (247 KB) SDS (252 KB)

COA (255 KB) HNMR (169 KB) LCMS (115 KB)

Handling Instructions (2659 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Siremadlin (R Enantiomer)1448867-42-2NVP-HDM201 (R Enantiomer) HDM201 (R Enantiomer)OthersInhibitorinhibitorinhibit

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Siremadlin (R Enantiomer) (Synonyms: NVP-HDM201 (R Enantiomer); HDM201 (R Enantiomer))

Customer Review

Other Forms of Siremadlin (R Enantiomer):

Biological Activity

Purity & Documentation

Customer Review

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

Keywords:

Your Recently Viewed Products:

Customer Review

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