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Siremadlin (R Enantiomer)  (Synonyms: NVP-HDM201 (R Enantiomer); HDM201 (R Enantiomer))

Cat. No.: HY-18658A Purity: 99.12%
COA Handling Instructions

Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

For research use only. We do not sell to patients.

Siremadlin (R Enantiomer) Chemical Structure

Siremadlin (R Enantiomer) Chemical Structure

CAS No. : 1448867-42-2

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 484 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 484 In-stock
1 mg USD 220 In-stock
5 mg USD 440 In-stock
10 mg USD 660 In-stock
50 mg USD 1950 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Siremadlin (R Enantiomer):

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Siremadlin R Enantiomer (NVP-HDM201 R Enantiomer) is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific MDM-2/p53 inhibitor.

Molecular Weight







O=C1N(C2=CC(Cl)=CN(C)C2=O)[[email protected]](C3=CC=C(Cl)C=C3)C4=C1N=C(C5=CN=C(OC)N=C5OC)N4C(C)C


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 56.75 mg/mL (102.18 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8005 mL 9.0024 mL 18.0047 mL
5 mM 0.3601 mL 1.8005 mL 3.6009 mL
10 mM 0.1800 mL 0.9002 mL 1.8005 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.19%

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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