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- Rutaceae ExtractOther Families ExtractPteridaceae Extract
- Pteris livida Mett.
Pteris livida Mett.
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Pteris livida Mett. (6)
- Formula: C21H22O6
- Molecular Weight: 370.40
β,β-Dimethylacrylalkannin (Arnebin 1) is an orally active FGFR1 inhibitor (IC50=2.5 μM) and the main active component of Lithospermum erythrorhizon. β,β-Dimethylacrylalkannin blocks downstream signaling by binding to the ATP pocket of FGFR1, and regulates the CDK1/Cdc25C pathway and ROS-JNK axis, thereby inducing G2/M phase arrest, necrosis and apoptosis in cancer cells, and inhibiting tumor proliferation. β,β-Dimethylacrylalkannin also acts as a colistin adjuvant to disrupt the cell membrane of Gram-negative bacteria. β,β-Dimethylacrylalkannin exhibits significant tumor-inhibitory effects with no obvious toxicity in PDX models, but chronic exposure to high doses may alter the relative lung/liver weights of rats, while acute exposure to high doses causes responses such as reduced motor activity. β,β-Dimethylacrylalkannin finds wide application in studies related to hepatocellular carcinoma, colorectal cancer, colistin-resistant bacterial infections, hepatitis and psoriasis.
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- Formula: C26H38O9
- Molecular Weight: 494.57
ent-9-Hydroxy-15-oxokaur-16-en-19-oic acid β-D-glucopyranosyl ester is a natural diterpene.
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- Formula: C26H38O10
- Molecular Weight: 510.57
1H-2,10a-Ethanophenanthrene, kaur-16-en-18-oic acid deriv. is a derivated compound isolated from the Pteridaceae plants of Costa Rica .
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- Formula: C14H11NO2
- Molecular Weight: 225.24
1-Hydroxy-N-methylacridone is an acridone alkaloid from Boronia lanceolate.
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- Formula: C13H9NO3
- Molecular Weight: 227.22
1,7-Dihydroxyacridone is a natural product that can be isolated from Boronia lanceolata.
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- Formula: C21H22O6
- Molecular Weight: 370.40
β,β-Dimethylacrylalkannin (Standard) (Arnebin 1 (Standard)) is the analytical standard of β,β-Dimethylacrylalkannin (HY-N5112A). This product is intended for research and analytical applications. β,β-Dimethylacrylalkannin (Arnebin 1) is a napthoquinone isolated from Alkanna cappadocica , increases collagen and involucrin content in skin cells.
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