2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0275S1
    Oxytetracycline-d3 98%
    Oxytetracycline-d3 is the deuterium labeled Oxytetracycline (HY-B0275). Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.
    Oxytetracycline-d3
  • HY-B0277AR
    Vidarabine phosphate (Standard) 29984-33-6
    Vidarabine phosphate (ara-AMP; ara-A 5'-monophosphate) (Standard) is the analytical standard of Vidarabine phosphate. This product is intended for research and analytical applications. Vidarabine phosphate is a purine nucleoside antiviral agent and a prodrug of Vidarabine (HY-B0277). Vidarabine phosphate is rapidly converted into the antiviral active Vidarabine in vivo, which selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis.
    Vidarabine phosphate (Standard)
  • HY-B0330S1
    (S)-Ofloxacin-d3 2208780-63-4 98.0%
    (S)-Ofloxacin-d3 is the deuterium labeled Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    (S)-Ofloxacin-d3
  • HY-B0333S2
    Sulfamethizole-d4-1 2470130-12-0 98%
    Sulfamethizole-d4-1 is the deuterium labeled Sulfamethizole (HY-B0333). Sulfamethizole is a sulfathiazole antibiotic. Sulfamethizole inhibits the synthesis of folic acid and thymine, and selectively suppresses Photobacterium phosphoreum bioluminescence. Sulfamethizole exerts antibacterial activity against Escherichia coli-mediated urinary tract infections but no activity against sulII gene-positive Escherichia coli. Sulfamethizole is applicable for the research of urinary tract infections and Photobacterium phosphoreum bioluminescence mechanisms.
    Sulfamethizole-d4-1
  • HY-B0337S2
    Sulfadimethoxine-13C6 1334378-48-1 98%
    Sulfadimethoxine-13C6 is the 13C-labeled Sulfadimethoxine. Sulfadimethoxine (Sulphadimethoxine) is a sulfonamide antibiotic used to treat many infections.
    Sulfadimethoxine-13C6
  • HY-B0338AR
    Rimantadine hydrochloride (Standard) 1501-84-4
    Rimantadine (hydrochloride) (Standard) is the analytical standard of Rimantadine (hydrochloride). This product is intended for research and analytical applications. Rimantadine is an orally active inhibitor for M2 protein, that blocks the hydrogen ion channel activity, prevents the entry and replication of the virus, and exhibits board-spectrum antiviral activity.
    Rimantadine hydrochloride (Standard)
  • HY-B0343AS
    Sarafloxacin-d8 hydrochloride 2733145-07-6 98%
    Sarafloxacin-d8 (A-56620-d8) hydrochloride is the deuterium labeled Sarafloxacin hydrochloride. Sarafloxacin hydrochloride (A-56620 hydrochloride) is a quinolone antibiotic drug.
    Sarafloxacin-d8 hydrochloride
  • HY-B0356AR
    Ciprofloxacin monohydrochloride (Standard) 93107-08-5 98%
    Ciprofloxacin (monohydrochloride) (Standard) is the analytical standard of Ciprofloxacin (monohydrochloride). This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin monohydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[4].
    Ciprofloxacin monohydrochloride (Standard)
  • HY-B0356AS
    Ciprofloxacin-d8 hydrochloride hydrate 98%
    Ciprofloxacin-d8 (hydrochloride hydrate) is the deuterium labeled Ciprofloxacin hydrochloride monohydrate. Ciprofloxacin hydrochloride monohydrate is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin-d8 hydrochloride hydrate
  • HY-B0356BS
    Ciprofloxacin-d8 hydrochloride monohydrate 98%
    Ciprofloxacin-d8 (hydrochloride monohydrate) is the deuterium labeled Ciprofloxacin (hydrochloride monohydrate). Ciprofloxacin hydrochloride is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
    Ciprofloxacin-d8 hydrochloride monohydrate
  • HY-B0364AS
    Dyclonine-d9 hydrochloride 98%
    Dyclonine-d9 (hydrochloride) is deuterium labeled Dyclonine (hydrochloride). Dyclonine hydrochloride (Dyclocaine hydrochloride) is an effective component of Runhou tablets. Dyclonine hydrochloride has significant bactericidal and fungicidal activity.
    Dyclonine-d9 hydrochloride
  • HY-B0398AR
    Nalidixic acid sodium salt (Standard) 3374-05-8 98%
    Liquiritin (Standard) is the analytical standard of Liquiritin. This product is intended for research and analytical applications. Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity.
    Nalidixic acid sodium salt (Standard)
  • HY-B0402R1
    Amantadine in Methanol (Standard) 768-94-5 98%
    Amantadine in Methanol (Standard) is the solution of Amantadine (Standard). This product is intended for research and analytical applications. Amantadine (1-Adamantanamine) is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine also has anti-orthopoxvirus and anticancer activity. Amantadine can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research[4].
    Amantadine in Methanol (Standard)
  • HY-B0421AR
    Mycophenolic acid sodium (Standard) 37415-62-6 98%
    Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects.
    Mycophenolic acid sodium (Standard)
  • HY-B0441AR
    Tobramycin sulfate (Standard) 49842-07-1
    Tobramycin (sulfate) (Standard) is the analytical standard of Tobramycin (sulfate). This product is intended for research and analytical applications. Tobramycin sulfate (Nebramycin Factor 6 sulfate) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms[1].
    Tobramycin sulfate (Standard)
  • HY-B0450AG
    Ciclopirox olamine (GMP) 41621-49-2 98%
    Ciclopirox (olamine) (GMP) is Ciclopirox olamine (HY-B0450A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Ciclopirox (HOE296b) is a synthetic antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic.
    Ciclopirox olamine (GMP)
  • HY-B0454AS
    Miconazole-d5 nitrate (2,4-Dichlorobenzyloxy-d5) 1398065-80-9 98%
    Miconazole-d5 (nitrate) (2,4-Dichlorobenzyloxy-d5) is the deuterium labeled Miconazole nitrate. Miconazole nitrate (R18134 nitrate) is an imidazole antifungal agent. Miconazole nitrate also has antibacterial effects.
    Miconazole-d5 nitrate (2,4-Dichlorobenzyloxy-d5)
  • HY-B0454S2
    Miconazole-d2 2140316-33-0 98%
    Miconazole-d2 is the deuterium labeled Miconazole. Miconazole (R18134) is an imidazole antifungal agent. Miconazole also has antibacterial effects.
    Miconazole-d2
  • HY-B0455AR
    Lomefloxacin (Standard) 98079-51-7 98%
    Lomefloxacin (Standard) is the analytical standard of Lomefloxacin. This product is intended for research and analytical applications. Lomefloxacin (SC47111A) is a broad-spectrum quinolone antibiotic, with antimicrobial activity. Lomefloxacin is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc..
    Lomefloxacin (Standard)
  • HY-B0462AS
    Azelastine-13C,d3 1217019-80-1 98%
    Azelastine-13C,d3 is deuterium labeled Azelastine. Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2.
    Azelastine-13C,d3
Cat. No. Product Name / Synonyms Application Reactivity