Others

(S)-E3 ligase Ligand 30 is an E3 ligand that can be used for the synthesis of PROTACs, such as PRT3789 epimer (HY-159607A).

N6-[(6-Aminohexyl)carbamoylmethyl]-ADP is an analog of ADP (HY-W010918), which can be obtained by alkylating ADP.

URAT1&XO inhibitor 3 (compound 27) is an orally active anti-gout agent targeting XO (IC₅₀: 35 nM) and URAT1 (IC₅₀: 31 nM). URAT1&XO inhibitor 3 has good pharmacological and pharmacokinetic (PK) characteristics and in vivo safety.

PRT3789 epimer is an epimer of PRT3789 (HY-159607). PRT3789 is a selective SMARCA2 PROTAC degrader.

Met-AMS (Compound 50) is a sulfonamide analog of methionyl-adenylate (Met-AMP) and an inhibitor of isoleucyl-tRNA synthetase (IleRS) with an IC₅₀ of 7 nM.

PNPLA3 modifier 1 (compound 10) is a Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifier, with a geometric mean EC₅₀ of 4.9 nM.

Lipid R6 is a lipid molecule that can be used to synthesize liposomes and is the lipid component in lipid nanoparticle (LNP) systems.

D-Val-L-Cit-PAB is an ADC connector that can be used to construct ADCs.

6-(4-Azidobutanamido) hexanoic acid is a PROTAC Linker that can be used to synthesize the PROTAC molecule NR-11c (HY-159798).

Filricianine sodium is an hydrophilic fluorochrome. It can be conjugated to antibody with higher D/P ratio and widely used applications including western blotting, microscopy, flow cytometry, and cell based assays.

Nacresertib is a Ser/Thr Protease inhibitor.

IR-117-17 is an ionizable cationic amino lipid, targeting conducting airways of the lung. IR-117-17 could be degraded via esterase cleavage and thus be unlikely to accumulate upon repeated dosing. It can be used in research related to diseases that manifest outside alveolar spaces.

15-Hydroxystearic acid is a hydroxylated long-chain fatty acid with high binding affinity to SlSCPx-2.

16-Hydroxystearic acid is a long-chain hydroxy fatty acids that can be isolated from cucumber and flax leaves.

1,2-Didehydrotanshinone IIA is a moderate AChE and BChE inhibitor, with an IC₅₀ value of 5.98 μM for BChE. 1,2-Didehydrotanshinone IIA is a IDO inhibitor, with an IC₅₀ value of 4.68 µM μM.

GalNAc-5 phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.

Fmoc-Gly-Gly-Gly-NH-PEG4-C2-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs

Creatinol (hemisulfate) is the N-ethyl analogue of creatine. Creatinol (hemisulfate) can be used for various researches.

25,25-Difluoro-27-norcholestenoic acid is an LXRb ligand that disrupts the His435-Trp457 aromatic-aromatic interaction, destabilizing the H11-H12 region and favoring corepressor binding.

27-Norcholestenoic acid is an inverse agonist of LXRβ and LXRα that decreases basal luciferase activity and inhibits agonist-induced transactivation. 27-Norcholestenoic acid induces conformational changes in the AF-2 domain that favor corepressor over coactivator recruitment, thereby destabilizing the active receptor conformation. 27-Norcholestenoic acid downregulates FASN and SREBP-1a/c gene expression.