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Cat. No.: HY-159465A

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(S)-E3 ligase Ligand 30

(S)-E3 ligase Ligand 30 is an E3 ligand that can be used for the synthesis of PROTACs, such as PRT3789 epimer (HY-159607A).

For research use only. We do not sell to patients.

CAS No.: 2725913-38-0
Formula: C₂₅H₃₀N₄O₄S
Molecular Weight:482.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(S)-E3 ligase Ligand 30 Chemical Structure

CAS No.: 2725913-38-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
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Biological Activity

Description

(S)-E3 ligase Ligand 30 is an E3 ligand that can be used for the synthesis of PROTACs, such as PRT3789 epimer (HY-159607A)^[1].

IC₅₀ & Target^[1]

VHL

All Ligands for E3 Ligase Isoforms :

Chemical Information

CAS No. 2725913-38-0
Molecular Weight 482.60
Formula C₂₅H₃₀N₄O₄S
SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C([C@@H](C(C)C)C4=CC=NO4)=O)O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hulse M, et al. PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4-Mutated Cancers. Cancer Res. 2026;86(1):213-235. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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(S)-E3 ligase Ligand 30

All Ligands for E3 Ligase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-E3 ligase Ligand 30 Related Classifications

HY-159465A Related Classifications