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ADC Linkers Related Products (527)
Related Products (527)
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Sulfo DBCO-TFP Ester
0 ImagesCat. No.: HY-151789CAS No.: 2268816-76-6Sulfo DBCO-TFP Ester is a water-soluble, sulfo-containing click chemistry reagent. Sulfo DBCO-TFP Ester enables simple and efficient incorporation of sulfo-DBCO moieties onto amine-containing molecules.
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H2N-PEG2-N3 (TosOH)
0 ImagesCat. No.: HY-151768CAS No.: 2173092-98-1H2N-PEG2-N3 (TosOH) is a click chemistry reagent containing an Azide. N3-PEG2-Amine is used as a Click-chemistry linker in various applications. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Fmoc-D-Lys(pentynoyl)-OH
0 ImagesCat. No.: HY-151826CAS No.: 2576508-18-2
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N3-Cystamine-Suc-OSu
0 ImagesCat. No.: HY-151743CAS No.: 1987341-40-1N3-Cystamine-Suc-OSu is a click chemistry reagent containing an azide group. N3-Cystamine-Suc-OSu can be used for the research of various biochemical. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Fmoc-L-Asn(EDA-N3)-OH
0 ImagesCat. No.: HY-151829CAS No.: 2616562-74-2Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Fmoc-D-Aha-OH
0 ImagesCat. No.: HY-151669CAS No.: 1263047-53-5Fmoc-D-Aha-OH is a click chemistry reagent containing an azide. Fmoc-D-Aha-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Fmoc-PEG6-Val-Cit-PAB-OH
0 ImagesCat. No.: HY-W800623CAS No.: 2055024-57-0Fmoc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
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D-Val-L-Cit-PAB
0 ImagesCat. No.: HY-159797ACAS No.: 2088364-35-4D-Val-L-Cit-PAB is an ADC connector that can be used to construct ADCs.
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Azido-PEG2-CH2COOH CHA (Standard)
0 ImagesCat. No.: HY-108368ARCAS No.: 2098500-94-6Azido-PEG2-CH2COOH CHA (Standard) is the analytical standard of Azido-PEG2-CH2COOH (CHA) (HY-108368A). This product is intended for research and analytical applications. Azido-PEG2-CH2COOH (CHA) is a azido-modified PEG2 acid, can be used as a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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N3-D-Orn(Boc)-OH
0 ImagesCat. No.: HY-151764CAS No.: 2165877-62-1N3-D-Orn(Boc)-OH is a Boc-protected pentanoic amino acid derivative, can be used as a click chemistry reagent and has been used to synthesis antibody-drug conjugates (ADC). It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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NHS-Ala-Ala-Asn-active metabolite
0 ImagesCat. No.: HY-157338CAS No.: 2231135-69-4NHS-Ala-Ala-Asn-active metabolite is a cleavable antibody-drug conjugate (ADC) linker for synthesis of kinesin spindle protein (KSP)inhibitor.
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N3-PhAc-OH
0 ImagesCat. No.: HY-151845CAS No.: 62893-37-2N3-PhAc-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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N3-1,4-cis-CHC-OH
0 ImagesCat. No.: HY-151856CAS No.: 863222-21-3N3-1,4-cis-CHC-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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DACN(Tos,Suc-OH)
0 ImagesCat. No.: HY-151766CAS No.: 2109751-68-8DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity.
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Fmoc-3VVD-OH (Standard)
0 ImagesCat. No.: HY-78921RCAS No.: 863971-44-2Fmoc-3VVD-OH (Standard) is the analytical standard of Fmoc-3VVD-OH (HY-78921). This product is intended for research and analytical applications. Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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(2S,3R)-H-Abu(3-N3)-OH hydrochloride
0 ImagesCat. No.: HY-151836CAS No.: 2737202-63-8(2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. (2S,3R)-H-Abu(3-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Mal-AMCHC-N-Propargylamide
0 ImagesCat. No.: HY-151752CAS No.: 2027476-42-0Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry.
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Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP
0 ImagesCat. No.: HY-141153CAS No.: 2055042-82-3Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a cleavable linker for synthesis of antibody-drug conjugates (ADCs).
