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ADC Linkers Related Products (527)
Related Products (527)
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N-[S-Trityl-L-cysteinyl]glycine
![N-[S-Trityl-L-cysteinyl]glycine](https://file.medchemexpress.com/product_pic/hy-w108635.gif "Click to View N-[S-Trityl-L-cysteinyl]glycine Product Detail")
0 ImagesCat. No.: HY-W108635CAS No.: 26988-61-4N-[S-Trityl-L-cysteinyl]glycine is a cleavable ADC linker.
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(2R,4R)-H-D-Pro(4-N3)-OH hydrochloride
0 ImagesCat. No.: HY-151839CAS No.: 2737202-69-4(2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent containing an azide group. (2R,4R)-H-D-Pro(4-N3)-OH (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N3-Aca-Aca-OH
0 ImagesCat. No.: HY-151861CAS No.: 866363-71-5
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Fmoc-L-Phe(4-NH-Poc)-OH
0 ImagesCat. No.: HY-151825CAS No.: 2576508-07-9Fmoc-L-Phe(4-NH-Poc)-OH is a click chemistry reagent containing an azide group. Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry.
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(2S,4S)-H-L-Pro(4-N3)-OH
0 ImagesCat. No.: HY-151865CAS No.: 892128-58-4(2S,4S)-H-L-Pro(4-N3)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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N3-D-Lys(Fmoc)-OH
0 ImagesCat. No.: HY-151749CAS No.: 1994300-35-4N3-D-Lys(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry is a powerful chemical reaction with excellent bioorthogonality features: biocompatible, rapid and highly specific in biological environments. N3-D-Lys(Fmoc)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N3-L-Dab(Fmoc)-OH
0 ImagesCat. No.: HY-151779CAS No.: 2250436-44-1N3-L-Dab(Fmoc)-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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SCO-PEG3-Maleimide
0 ImagesCat. No.: HY-156318CAS No.: 2141976-35-2SCO-PEG3-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
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N-Boc-N-methyl-D-Valinol
0 ImagesCat. No.: HY-41063CAS No.: 2165479-27-4N-Boc-N-methyl-D-Valinol is an ADC linker with BOC protecting group.
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N3-TFBA-O2Oc
0 ImagesCat. No.: HY-151744CAS No.: 1993119-45-1N3-TFBA-O2Oc is a click chemistry reagent containing an azide group and an aryl group. Aryl azides are well-known precursors of nitrenes and have been introduced by Fleet et al. as versatile photoaffinity labeling agents to probe biological receptors. This type of compounds has been used as photo-cross linker (λmax=258 nm) in estrogen receptor studies and for direct surface coating of carbon and organic based polymers. N3-TFBA-O2Oc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Fmoc-PEG2-Val-Cit-PAB-OH
0 ImagesCat. No.: HY-W800621CAS No.: 2055024-59-2Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine for use in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
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MC-Val-Ala-NHS ester
0 ImagesCat. No.: HY-W591479CAS No.: 1895916-22-9MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.
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N3-L-Dap(Boc)-OH
0 ImagesCat. No.: HY-151736CAS No.: 1932432-15-9N3-L-Dap(Boc)-OH is a non-natural amino acid building block specially designed for solid-phase peptide synthesis and click chemistry. N3-L-Dap(Boc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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Biotin-MeTz
0 ImagesCat. No.: HY-151714CAS No.: 1802883-51-7Biotin-MeTz shiyi is a click chemistry reagent with a terminal methyltetrazine group. Biotin-MeTz shiyi, as a biotin derivative, can be used for the preparation of biotinylated conjugates.
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Benzyl 2-cyclopropyl-2-hydroxyacetate
0 ImagesBenzyl 2-cyclopropyl-2-hydroxyacetate is a glycolate ester and a Camptothecin (HY-16560) derivative payload component used for the preparation of antibody-drug conjugates. Benzyl 2-cyclopropyl-2-hydroxyacetate functions as the cytotoxic payload moiety of the conjugate linker. Benzyl 2-cyclopropyl-2-hydroxyacetate can be used in cancer research.
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Fmoc-PEG4-GGFG-CH2-O-CH2-Cbz
0 ImagesFmoc-PEG4-GGFG-CH2-O-CH2-Cbz is a cleavable ADC linker containing 4 units of PEG, which can be used to synthesize active antibody conjugation molecules (ADC).
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Alkyne-Val-Cit-PAB-OH
0 ImagesCat. No.: HY-164275CAS No.: 2748039-76-9Alkyne-Val-Cit-PAB-OH is a cleavable ADC linker.
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Boc-Gly-Sar-OH
0 ImagesCat. No.: HY-W108137CAS No.: 133498-97-2Boc-Gly-Sar-OH is a cleavable ADC linker.
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DAPOA DCHA
0 ImagesCat. No.: HY-151783ADAPOA DCHA is a click chemistry reagent containing an azide. DAPOA DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or click-chemistry. This material can be used as a building block for dendrimeric structures. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
