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Isotope-Labeled Compounds
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Isotope-Labeled Compounds Related Products (11098)
Related Products (11098)
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Glibenclamide-13C6
0 ImagesCat. No.: HY-15206S2Synonyms: Glyburide-13C6Glibenclamide-13C6 (Glyburide-13C6) is 13C labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR). Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability. Glibenclamide can induce autophagy. -
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1-Octanol-d5
0 ImagesCat. No.: HY-W032013S3CAS No.: 3028869-76-0Synonyms: Octanol-d51-Octanol-d5 is deuterated labeled 1-Octanol (HY-W032013). 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol is a highly attractive biofuel with diesel-like properties. -
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Hypoxanthine-13C2,15N-1
0 ImagesCat. No.: HY-N0091S4CAS No.: 1246820-04-1Synonyms: Purin-6-ol-13C2,15N-1; Sarcine-13C2,15N-1Hypoxanthine-13C2,15N-1 is a 15N-labeled and 13C-labled Hypoxanthine (HY-N0091). Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia. -
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Irbesartan-d7
0 ImagesCat. No.: HY-B0202S3Synonyms: SR-47436-d7; BMS-186295-d7Irbesartan-d7 is deuterated labeled Irbesartan (HY-B0202). Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease. -
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3-Phenyl-9H-carbazole-d12
0 ImagesCat. No.: HY-W103764S1CAS No.: 2851075-04-03-Phenyl-9H-carbazole-d12 is the deuterium labeled 3-Phenyl-9H-carbazole. -
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Bis(1-chloro-2-propyl) phosphate-d12
0 ImagesCat. No.: HY-W653929CAS No.: 1870073-89-4Synonyms: BCIPP-d12Bis(1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure. -
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N-6-[rel-(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinamine-Sonidegib-d8
0 ImagesCat. No.: HY-157571S -
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Epi lovastatin-d3
0 ImagesCat. No.: HY-N0504SCAS No.: 1330264-51-1Epi Lovastatin-d3 is the deuterium labeled Lovastatin. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. -
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L-Serine-15N,d3
0 ImagesCat. No.: HY-N0650S9Synonyms: (-)-Serine-15N,d3; (S)-Serine-15N,d3L-Serine-15N,d3 is the deuterium and 15N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation. -
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Menthofuran-13C2
0 ImagesCat. No.: HY-N9484SCAS No.: 3028870-62-1Menthofuran-13C2 is the 13C-labeled Menthofuran, 84% (HY-N9484). Menthofuran, 84% is an orally active modulator of pulegone reductase with gastroprotective activity, and it is the metabolite of (R)-(+)-Pulegone. Menthofuran, 84% reduces the transcriptional level of pulegone reductase in immature peppermint leaves, increases the content of pulegone in peppermint essential oil, and regulates the biosynthesis of peppermint essential oil through a feedforward-like inhibition mechanism. Menthofuran, 84% decreases total gastric acidity, restores non-protein thiol levels, inhibits lipid peroxidation, and reduces myeloperoxidase activity, with its mechanism of action related to the NOS pathway and endogenous prostaglandins. Menthofuran, 84% can be used in studies related to gastric ulcers. -
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Domperidone-d6
0 ImagesCat. No.: HY-B0411SCAS No.: 1329614-18-7Domperidone-d6 is the deuterium labeled Domperidone. Domperidone (R33812) is a selective dopamine-2 receptor antagonist. Domperidone acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine. -
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1,2,3,4,7,8,9-Heptachloro-dibenzofuran-13C12
0 ImagesCat. No.: HY-W748312CAS No.: 109719-94-01, 2, 3, 4, 7, 8, 9-Heptachloro-dibenzofuran- 13C12 is 13C labeled 1,2,3,4,7,8,9-Heptachlorodibenzo[b,d]furan. -
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3-Mercapto-3-methylbutan-1-ol-d6
0 ImagesCat. No.: HY-W012855SCAS No.: 162404-35-53-Mercapto-3-methylbutan-1-ol-d6 is the deuterium labeled 3-Mercapto-3-methylbutan-1-ol. -
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Clomiphene-d5 citrate
0 ImagesCat. No.: HY-118861AS1CAS No.: 1217200-17-3Synonyms: Clomifene-d5 citrate; (Z/E)-Enclomiphene-d5 citrate; (Z/E)-Enclomifene-d5 citrateClomiphene-d5 (citrate) is the deuterium labeled Enclomiphene citrate. Enclomiphene citrate is a potent and orally active oestrogen receptor antagonist, with antioestrogenic property. -
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Fluralaner-d2
0 ImagesCat. No.: HY-16973S5Synonyms: A1443-d2; AH252723-d2Fluralaner-d2 (A1443-d2) is deuterium labeled Fluralaner. Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels. -
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Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers)
0 ImagesCat. No.: HY-132379SCAS No.: 1189445-29-1Synonyms: MIN-102-d5; Hydroxypioglitazone-d5Hydroxy Pioglitazone-d5 (M-IV) (Mixture of-diastereomers) is the deuterium labeled Hydroxy Pioglitazone (M-IV) (Mixture of-diastereomers). -
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(E)-5-OAHSA-d17
0 ImagesCat. No.: HY-170010SCAS No.: 2714169-20-5(E)-5-OAHSA-d17 is deuterium labeled (E)-5-OAHSA. -
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Tofacitinib-13C
0 ImagesCat. No.: HY-40354S3Synonyms: Tasocitinib-13C; CP-690550-13CTofacitinib-13C (Tasocitinib-13C; CP-690550-13C) is the 13C-labeled Tofacitinib (HY-40354). Tofacitinib (Tasocitinib) is an orally active, blood-brain barrier permeable selective inhibitor of JAK1/JAK3. Tofacitinib blocks the JAK-STAT/NF-κB signaling pathway, inhibits cytokine signal transduction, phosphorylation of STAT1/STAT5, and suppresses innate and adaptive immune responses. Tofacitinib can be used in research related to major depressive disorder, rheumatoid arthritis, pulmonary diseases, systemic lupus erythematosus, and immune-mediated liver injury. -
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STEDTAEYSPF-(Lys-13C6,15N2) TFA
0 ImagesCat. No.: HY-P11536SSTEDTAEYSPF-(Lys-13C6,15N2) TFA is the 13C- and 15N-labeled STEDTAEYSPF. -
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Indapamide-13C,d3
0 ImagesCat. No.: HY-B0259S1CAS No.: 2934053-07-1Indapamide-13C,d3 is 13C and deuterium labeled Indapamide. Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy. -
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