Liposome
Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.
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Liposome Related Products (1076)
Related Products (1076)
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DOPE-PEG2000-Mal
0 ImagesCat. No.: HY-W440995Purity: 99.60%DOPE-PEG2000-Mal is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. It is also reactive with thiol at pH 6.5 tp 7.5 to form a stable thioether bond.
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98N12-5
0 Images98N12-5 is a novel multi-tail ionizable lipids that has been used for efficient in vivo siRNA-delivery to the liver.
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
0 Images1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE also acts as an immune response regulator and toxicity alleviator produced by Microcystis aeruginosa under Cu2+ stress.
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1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine
0 Images1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases.
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18:0,18:1 PS sodium
0 Images18:0,18:1 PS sodium is the dominant phosphatidylserine subtype in cells, exosomes and HIV particles. It is abundant in the brain and is essential for maintaining membrane structure, lipid raft organization and intracellular trafficking. 18:0,18:1 PS sodium mediates interleaflet membrane coupling through cholesterol-dependent interactions with very long-chain sphingolipids, and can induce the clustering of glycosylphosphatidylinositol-anchored proteins. In addition, clusters formed by the binding of 18:0,18:1 PS sodium to cholesterol not only facilitate the proper distribution of cholesterol in lipid bilayers, but also effectively protect cholesterol from oxidative damage.
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11-Mercaptoundecanoate-NHS
0 Images11-Mercaptoundecanoate-NHS is a lipid that can be used for the synthesis of Linker.
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DGDG
0 ImagesDGDG, a chloroplast lipid, is a bilayer-forming lipid. DGDG is important for photosynthesis, and can be used for drug delivery.
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DSPE-PEG2000-iRGD
0 ImagesCat. No.: HY-172494DSPE-PEG2000-iRGD is a PEG compound which composed of DSPE and an αv-integrins targeting peptide (iRGD). iRGD peptide binds to αv-integrins, and then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties. DSPE-PEG2000-iRGD can be used for agent delivery.
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eGFP mRNA-LNP (500 ng/μL)
0 ImagesCat. No.: HY-153231AeGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability.
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A18-Iso5-2DC18
0 ImagesCat. No.: HY-148488CAS No.: 2412492-09-0
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1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium
0 ImagesSynonyms: DMPS-Na; Dimyristoyl phosphatidylserine sodium1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium is an anionic phospholipid with myristic acid tails (14:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of liposome.
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NT1-O12B
0 ImagesCat. No.: HY-137499CAS No.: 2739805-63-9NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination.
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m-PEG-DMG (MW 2000)
0 Imagesm-PEG-DMG (MW 2000) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies.
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COVID-19 Spike Protein mRNA-LNP
0 ImagesCat. No.: HY-153235COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) containing mRNA encoding COVID-19 Spike Protein. COVID-19 Spike Protein undertakes the functions of virus binding with host cell receptors, thereby mediating the entry of COVID-19 virus into cells. COVID-19 Spike Protein is an important site of action for host neutralizing antibodies and a key target for vaccine design. COVID-19 Spike Protein mRNA-LNP can be used for RNA delivery, vaccine formulation and design targeting SARS-CoV-2.
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OF-Deg-Lin
0 ImagesCat. No.: HY-134782CAS No.: 1853202-95-5OF-Deg-Lin is an ionizable amino lipid used for the generation of Lipid nanoparticles (LNPs).
