2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Melatonin Receptor
  5. MT1 Isoform
  6. MT1 Agonist

MT1 Agonist

MT1 Agonists (4):

Cat. No. Product Name Effect Purity
  • HY-A0014
    Ramelteon
    		Agonist 99.87%
    Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively.
  • HY-138626
    ACH-000143
    		Agonist 98.65%
    ACH-000143 is a potent and orally active melatonin receptor agonist, with EC50 values of 0.06 nM and 0.32 nM for MT1 and MT2, respectively.
  • HY-147542
    Melatonin receptor agonist 1
    		Agonist
    Melatonin receptor agonist 1 (compound 20c) is a potent melatonin receptor (MT) agonist, with Ki values of 108 nM (MT2) and 1140 nM (MT1).
  • HY-100940
    6-Chloromelatonin
    		Agonist
    6-Chloromelatonin is a potent melatonin receptor agonist with greater metabolic stability than melatonin.