Prostaglandin Receptor
Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors. There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors. These receptors are named: DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor. The prostaglandins are a group of hormone-like lipid compounds that are derived enzymatically from fatty acids and have important functions in the animalbody. There are currently ten known prostaglandin receptors on various cell types.
Prostaglandin Receptor Isoform Specific Products
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Prostaglandin Receptor Inhibitors
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Prostaglandin Receptor Agonists
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Prostaglandin Receptor Antagonists
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Prostaglandin Receptor Activators
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Prostaglandin Receptor Modulators
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Prostaglandin Receptor Inducers
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Prostaglandin Receptor Degrader
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Prostaglandin Receptor Controls
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Prostaglandin Receptor Ligands
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Prostaglandin Receptor Related Products (766)
Related Products (766)
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Antibodies (2)
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Prostaglandin Receptor Isoform Comparison
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MED 27
0 ImagesCat. No.: HY-106398CAS No.: 104333-87-1MED 27 is an inhibitor of thromboxane synthase and thromboxane A2 receptors. MED 27 can inhibit rat platelet aggregation at doses much lower than that of Acetylsalicylic acid (HY-14654).
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9-deoxy-9-methylene Prostaglandin E2
0 ImagesCat. No.: HY-114947CAS No.: 61263-32-9Synonyms: 9-Deoxy-9-methylene PGE29-deoxy-9-methylene Prostaglandin E2 (9-deoxy-9-methylene PGE2) is a stable, isosteric analog of PGE2. 9-deoxy-9-methylene PGE2 retains the biological profile of PGE2 with fewer side effects. In the rat 9-deoxy-9-methylene PGE2 is equipotent to PGE2 in decreasing blood pressure. It also stimulates the gerbil colon and primate uterus at the same potency as PGE2.
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Prostaglandin F2α dimethyl amine
0 ImagesCat. No.: HY-114761CAS No.: 67508-09-2Prostaglandin F2α dimethyl amine is a Prostaglandin F2α (HY-12956) derivative. Prostaglandin F2α dimethyl amine is an antagonist for Prostaglandin F receptor (FP). Prostaglandin F2α dimethyl amine blocks the cardiovascular responses induced by orexin and Arachidonic acid (HY-109590).
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Prostaglandin E1 ethanolamide
0 ImagesCat. No.: HY-137567CAS No.: 210976-81-1Prostaglandin E1 ethanolamide is an analog of prostaglandin E1 (PGE1) and may effectively inhibit GLI2-induced expression of target genes, including Gli1 and Ptch1, and tumor growth.
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Tetranor-PGDM
0 ImagesCat. No.: HY-126986CAS No.: 70803-91-7Tetranor-PGDM is an abundant urinary metabolite reflects biosynthesis of prostaglandin D2.
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iso-Samixogrel
0 ImagesCat. No.: HY-123400ACAS No.: 133276-52-5Synonyms: iso-DTTX30; iso-DT-TX 30 SEIso-Samixogrel (iso-DTTX30) is a combined thromboxane A2 receptor blocker and thromboxane synthetase inhibitor that exhibits potent antithrombotic activity. Iso-Samixogrel effectively eliminates recurrent arterial thrombus formation and inhibits collagen-induced platelet aggregation ex vivo. Iso-Samixogrel also prolongs sublingual bleeding time, demonstrating its biological efficacy in managing thrombosis.
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AFP-07 free acid
0 ImagesCat. No.: HY-129293CAS No.: 788799-13-3AFP-07 free acid is a derivative of 7, 7-difluoroprostacyclic and is a highly potent and selective prostacyclin receptor IP receptor agonist with a Ki value of 0.561 nM.
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20-ethyl Prostaglandin F2α
0 ImagesCat. No.: HY-137504CAS No.: 36950-85-3Synonyms: ICI 74205; 20-ethyl PGF2α20-ethyl Prostaglandin F2α (ICI 74205; 20-ethyl PGF2α) is an analog of PGF2α and an arachidonic acid (HY-109590) metabolite.
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IPR agonist-1
0 ImagesCat. No.: HY-187539SCAS No.: 3085716-86-2IPR agonist-1 is a prostaglandin-based IP receptor agonist. IPR agonist-1 binds to the IP receptor, forms hydrogen bonds with Tyr75-Ser168-Arg279, and undergoes π-π stacking with Tyr281, thereby triggering downstream signaling pathways. IPR agonist-1 inhibits ADP (Adenosine 5'-diphosphate) (HY-W010918)-induced platelet aggregation in rabbit platelet-rich plasma. IPR agonist-1 can be used in the research of pulmonary arterial hypertension.
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PSA1 (141-150)
0 ImagesCat. No.: HY-P1813CAS No.: 160215-60-1Synonyms: PSA-PeptidePSA1 (141-150), a prostate specific antigen 1 peptide, is used in the immunotherapy of cancer experiments.
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MB-28767
0 ImagesCat. No.: HY-118820CAS No.: 80558-61-8Synonyms: M&B 28767MB-28767 (M&B 28767) is an EP3 receptor agonist.
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15(S)-15-methyl Prostaglandin D2
0 ImagesCat. No.: HY-137355CAS No.: 85280-90-6Synonyms: 15(S)-15-Methyl PGD215(S)-15-methyl Prostaglandin D2 (15(S)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. In contrast to PGD2, 15(S)-15-methyl PGD2 induces vasoconstriction and increases systemic blood pressure with much reduced inhibitory activity on ADP-induced platelet aggregation. It also exhibits strong antifertility activity in hamsters (200-fold more potent than PGD2).
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FR191413
0 ImagesCat. No.: HY-118945CAS No.: 194928-55-7FR191413 is a selective bradykinin B2 receptor agonist that stimulates prostaglandin E2 production in WI-38 cells and activates BK B2 receptor-mediated pathways such as vasodilation and organ protection. FR191413 competitively binds to [3H]-BK in guinea pig ileum (GPI) membranes and CHO cells transfected with the human BK B2 receptor, with IC50 values of 20.0 nM and 2.60 nM, respectively. FR191413 can be used in research related to cardiovascular diseases and diabetes, including hypertension, myocardial hypertrophy, myocardial infarction, arrhythmias, and diabetic nephropathy.
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Prostaglandin F2a/BSA
0 ImagesCat. No.: HY-163552Prostaglandin F2a/BSA is an antigen-adjuvant conjugate formed by the conjugation of Prostaglandin F2a with Bovine Serum Albumin (BSA). By conjugating the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes and can enhance cross-presentation as well as the generation of antigen-specific T cells.
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PGF2α analogue-1
0 ImagesCat. No.: HY-136627CAS No.: 291303-34-9
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FCE 20700
0 ImagesCat. No.: HY-W747307CAS No.: 89648-76-0FCE 20700 is an orally active PGE2 analogue. FCE 20700 can prevent gastric mucosal damage and in inhibit gastric acid and pepsin secretion. FCE 20700 can be used for the research of gastrointestinal ulcer.
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Isbogrel
0 ImagesCat. No.: HY-119890CAS No.: 89667-40-3Synonyms: CV-4151Isbogrel (CV-4151) is a potent selective inhibitor of thromboxane A2 synthase. Isbogrel has oral activity and inhibits blood TXA2 generation with an ID50 value of 0.04 mg/kg.
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Gemeprost
0 ImagesCat. No.: HY-106534CAS No.: 64318-79-2Synonyms: Preglandin; SC-37681Gemeprost (Preglandin), a Prostaglandin E1 (HY-B0131) analogue, is a potent antiprogestogen drug. Gemeprost has the potential for second trimester abortion research.
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FR181157
0 ImagesCat. No.: HY-120123CAS No.: 171046-15-4FR181157, an orally active PGI2 agonist activity with especially good pharmacokinetic properties.
