2. Signaling Pathways
  3. GPCR/G Protein
    MAPK/ERK Pathway
  4. Ras
  5. Ras Isoform
  6. Ras Antagonist

Ras Antagonist

Ras Antagonists (3):

Cat. No. Product Name Effect Purity
  • HY-136172
    ESI-08
    		Antagonist 98.74%
    ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation.
  • HY-15702
    HJC0350
    		Antagonist 98.11%
    HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.
  • HY-117064
    NY-0173
    		Antagonist
    NY-0173 is an antagonist of Exchange proteins directly activated by cAMP (EPAC), with IC50s of 3.5 μM (EPAC2)and 4.0 μM (EPAC1) respectively. NY-0173 can be used to elucidate the biological functions of EPAC.