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Ras Antagonist

ESI-08

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Cat. No.: HY-136172

CAS No.: 301177-43-5

Purity: 98.74%

ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC₅₀ of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation.
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HJC0350

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Cat. No.: HY-15702

CAS No.: 885434-70-8

Purity: 98.11%

HJC0350 is a potent and specific EPAC2 antagonist with an IC₅₀ of 0.3 μM.
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NY-0173

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Cat. No.: HY-117064

CAS No.: 1801911-86-3

NY-0173 is an antagonist of Exchange proteins directly activated by cAMP (EPAC), with IC₅₀s of 3.5 μM (EPAC2)and 4.0 μM (EPAC1) respectively. NY-0173 can be used to elucidate the biological functions of EPAC.
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Cat. No.
Purity
Feature
CAS No.
Storage
Solvent & Solubility
Appearance
Initial Source
Emission (Em)
Excitation (Ex)
Sequence Shortening
Isotype
Gene ID
Accession
Application
Reconsititution
Molecular Weight	molecularWeight
Enzyme Activity
Specific Activity
In Vitro
In Vivo
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