2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Fructose-1,6-bisphosphate aldolase
  5. Fructose-1,6-bisphosphate aldolase Inhibitor

Fructose-1,6-bisphosphate aldolase Inhibitor

Fructose-1,6-bisphosphate aldolase Inhibitors (5):

Cat. No. Product Name Effect Purity
  • HY-148189
    Aldometanib
    		Inhibitor 99.65%
    Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis.
  • HY-148077
    Phosphoglycolohydroxamic acid
    		Inhibitor 98.0%
    Phosphoglycolohydroxamic acid is a potent aldolase and triose-phosphate isomerase inhibitor. Phosphoglycolohydroxamic acid can be used in the research of antibacterial and antifungal area.
  • HY-181267
    ALDOA-IN-1
    		Inhibitor 98.46%
    ALDOA-IN-1 is an aldolase A(ALDOA) inhibitor. ALDOA-IN-1 directly inhibits ALDOA enzymatic activity, thereby reducing lactate production, downregulating HIF-1α expression, and ultimately inducing cancer cell apoptosis. ALDOA-IN-1 can be used for research on colorectal cancer.
  • HY-143899
    FBA-IN-1
    		Inhibitor 98.79%
    FBA-IN-1 (compound 2a11) is a first-in-class, covalent and allosteric inhibitor of fructose-1,6-bisphosphate aldolase from Candida albicans (CaFBA). FBA-IN-1 inhibits the growth of Azole-resistant strains 103 with the MIC80 of 1 μg/mL.
  • HY-180388
    Stibophen
    		Inhibitor
    Stibophen is a potent antiparasitic agent is effective against Litomosoides carinii, Dipetalonema witei, and Brugia pahangi. Stibophen inhibits lactate accumulation and phosphofructokinases (PFK) activity in adult filariids. Stibophen also inhibits Ascaris and Hymenolepis diminuta PFK without inhibiting mammalian liver PFK. Stibophen can be used for the research of schistosomiasis and filariid infections.