2. Signaling Pathways
  3. Immunology/Inflammation
  4. CD1

CD1

 

CD1 Related Products (21):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-102022
    α-Galactosylceramide
    α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor).
    α-Galactosylceramide
  • HY-P990273
    Anti-Mouse CD38 Antibody (NIMR5)
    		Inhibitor
    Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of CD1d protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer.
    Anti-Mouse CD38 Antibody (NIMR5)
  • HY-P990287
    Anti-Mouse CD1d Antibody (19G11)
    		Inhibitor
    Anti-Mouse CD1d Antibody (19G11) is a rat-derived IgG1 type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (19G11) can neutralize CD1d and inhibit the activation of invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (19G11) can be used for the researches of inflammation and immunology, such as colitis.
    Anti-Mouse CD1d Antibody (19G11)
  • HY-144012A
    DPPE-PEG350
    		Antagonist 99%
    DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells. DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.
    DPPE-PEG350
  • HY-P990807
    Anti-Mouse CD1d Antibody (20H2 (HB323))
    		Inhibitor
    Anti-Mouse CD1d Antibody (20H2 (HB323)) is a rat-derived IgG1 κ type antibody inhibitor, targeting to mouse CD1d. Anti-Mouse CD1d Antibody (20H2 (HB323)) can block CD1d and neutralize invariant natural killer T (iNKT) cells. Anti-Mouse CD1d Antibody (20H2 (HB323)) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma, L. monocytogenes infection and arthritis.
    Anti-Mouse CD1d Antibody (20H2 (HB323))
  • HY-P992059
    Anti-Mouse CD1d Antibody (1B1)
    		Antagonist
    Anti-Mouse CD1d Antibody (1B1) is an antibody targeting mouse CD1d (Kd=12.5 nM). By inserting into the lipid-binding groove of CD1d, Anti-Mouse CD1d Antibody (1B1) overlaps with the binding sites of type I and type II NKT cell receptors (TCR), thereby effectively blocking TCR-mediated interactions. Anti-Mouse CD1d Antibody (1B1) activates antigen-presenting cells such as dendritic cells and macrophages, induces them to release IL-12p70, and increases the levels of key cytokines including IL-12, IFN-γ and IFN-α in mouse serum. Anti-Mouse CD1d Antibody (1B1) can be used in studies related to renal cancer, breast cancer and colon adenocarcinoma. When combined with anti-DR5 or anti-CD137 antibodies and chemotherapeutic drugs, Anti-Mouse CD1d Antibody (1B1) exhibits significant tumor inhibitory and even eradication effects in mice.
    Anti-Mouse CD1d Antibody (1B1)
  • HY-181739
    GCB-27a
    		Activator
    GCB-27a is a CD1d-binding immunostimulant and antitumor agent. GCB-27a binds to CD1d to form a stable complex and presents it to NKT cells, enhancing hydrophobic interactions within the A' pocket of CD1d through branched-chain conformation restriction. GCB-27a induces a Th1-biased immune response, drives IFN−γ production and limits IL-4 levels. GCB-27a is applicable to research related to melanoma lung metastasis.
    GCB-27a
  • HY-P991891
    Anti-CD1d Antibody
    Anti-CD1d Antibody is an antibody against human CD1d. Recommend Isotype Controls:?Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-CD1d Antibody
  • HY-162727
    GCS-12
    		Activator
    GCS-12 is a Th1/2-balanced sulfonamide glycolipid with improved interaction with CD1d. GCS-12 is an agonist for natural killer T (NKT) cell, that induces the secretion of cytokine IFN-γ and IL-4, and exhibits immunomodulatory and anti-tumor activities in mice.
    GCS-12
  • HY-P990869
    Anti-CD1a Antibody (OKT-6)
    		Inhibitor
    Anti-CD1a Antibody (OKT-6) is an anti-human CD1a IgG1 monoclonal antibody. Anti-CD1a Antibody (OKT-6) blocks T cell activation by blocking CD1a function. Anti-CD1a Antibody (OKT-6) can reduce the production of IFN-γ. Anti-CD1a Antibody (OKT-6) can be used for researches on cancer and inflammation such as leukemia. The recommend isotype control of Anti-CD1a Antibody (OKT-6): Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-CD1a Antibody (OKT-6)
  • HY-P991846
    Anti-CD1d Antibody (D5)
    		Inhibitor
    Anti-CD1d Antibody (D5) reacts with the human CD1d. CD1d belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. Recommend Isotype Controls: Mouse IgG2b kappa, Isotype Control (HY-P99982).
    Anti-CD1d Antibody (D5)
  • HY-175365
    GCS-12–6
    		Ligand
    GCS-12–6 is a potent Th2-selective NKT cell agonist targeting CD1d protein. GCS-12–6 is promising for research of autoimmune diseases (e.g., inflammatory bowel disease, multiple sclerosis).
    GCS-12–6
  • HY-RS02201
    CD1C Human Pre-designed siRNA Set A
    		Inhibitor

    CD1C Human Pre-designed siRNA Set A contains three designed siRNAs for CD1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD1C Human Pre-designed siRNA Set A
  • HY-P991890
    Anti-CD1a Antibody
    Anti-CD1a Antibody is an antibody against human CD1a. Recommend Isotype Controls:?Mouse IgG1 kappa, Isotype Control (HY-P99977).
    Anti-CD1a Antibody
  • HY-RS02202
    CD1D Human Pre-designed siRNA Set A
    		Inhibitor

    CD1D Human Pre-designed siRNA Set A contains three designed siRNAs for CD1D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD1D Human Pre-designed siRNA Set A
  • HY-RS02199
    CD1A Human Pre-designed siRNA Set A
    		Inhibitor

    CD1A Human Pre-designed siRNA Set A contains three designed siRNAs for CD1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD1A Human Pre-designed siRNA Set A
  • HY-181740
    GCB-27b
    		Activator
    GCB-27b is an immunostimulant that binds to CD1d. GCB-27b forms a stable and long-lasting complex with CD1d, which is presented to the TCR of NKT cells to drive immune responses. GCB-27b induces a Th1-skewed immune response in *Mus musculus*, resulting in high expression of IFN−γ with restricted IL-4 levels. GCB-27b is applicable to research related to lung metastasis of melanoma.
    GCB-27b
  • HY-RS02200
    CD1B Human Pre-designed siRNA Set A
    		Inhibitor

    CD1B Human Pre-designed siRNA Set A contains three designed siRNAs for CD1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD1B Human Pre-designed siRNA Set A
  • HY-186103
    Glycolipid C34
    Glycolipid C34, α-GalCer (HY-102022) analog, is a CD1d-binding glycolipid antinfection agent. Glycolipid C34 mediates invariant natural killer T cell activation and increases the secretion of IFN-γ and IL-4. Glycolipid C34 promotes clearance of bacterial infections in murine models and enhances protective immunity against viral infections. Glycolipid C34 can be used for the research of bacterial infection, viral infection.
    Glycolipid C34
  • HY-102022R
    α-Galactosylceramide (Standard)
    α-Galactosylceramide (Standard) is the analytical standard of α-Galactosylceramide (HY-102022). This product is intended for research and analytical applications. α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor).
    α-Galactosylceramide (Standard)