2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D2254
    CTB probe-1
    CTB probe-1 (probe 1) a lysosome-targeting fluorogenic small-molecule probe for fluorescence imaging in living cells.
    CTB probe-1
  • HY-177645D
    Cy3 labled Marpinersen sodium
    Cy3 labled Marpinersen sodium is a Cy3 labled Marpinersen sodium.
    Cy3 labled Marpinersen sodium
  • HY-153492E
    Cy3 labled Olpasiran sodium
    Cy3 labled Olpasiran sodium is a Cy3 labled Olpasiran sodium.
    Cy3 labled Olpasiran sodium
  • HY-131510
    Chromoionophore XIII
    Chromoionophore XIII (SNARF-DE) is a pH senor that enables excitation with red light. Chromoionophore XIII functionality renders the indicator molecule lipophilic and water-insoluble but also prevents lactonization of the dye in an apolar environment.
    Chromoionophore XIII
  • HY-D0052
    5(6)-Carboxyeosin-diacetate
    5(6)-Carboxyeosin-diacetate is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    5(6)-Carboxyeosin-diacetate
  • HY-D3377
    HMRhoNox-M
    HMRhoNox-M (LysoRhoNox) is a selective fluorescent probe for labile Fe2+ with an orange fluorescence, and its excitation/emission wavelength is λₑₓ/λₑₘ = 555/575 nm. HMRhoNox-M undergoes N-oxide deoxygenation mediated by Fe2+, converting from a non-fluorescent spirocyclic closed form to a fluorescent quinone open form. HMRhoNox-M is used to detect labile Fe2+ in living cells.
    HMRhoNox-M
  • HY-D1531
    4-Methyl-2-phenylchromenylium tetrafluoroborate
    4-Methyl-2-phenylchromenylium tetrafluoroborate is a fluorescent dye.
    4-Methyl-2-phenylchromenylium tetrafluoroborate
  • HY-159156
    MAT2A inhibitor 6
    MAT2A inhibitor 6 (Compound 3N-h) is a specific MAT2A inhibitor with oral activity and yellow fluorescence (IC50=26 nM), capable of visualizing MAT2A both in vitro and in vivo (λex = 430 nm, λem = 585 nm). MAT2A inhibitor 6 can induce apoptosis and has anticancer activity, which can be used in cancer research.
    MAT2A inhibitor 6
  • HY-D2146
    Cy5-PEG3-TCO4
    Cy5-PEG3-TCO4 is a dye derivative of Cyanine 5 (Cy5) (HY-D0821) containing 3 PEG units. Cy5-PEG3-TCO4 utilizes its own TCO group to undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules bearing Tetrazine groups.
    Cy5-PEG3-TCO4
  • HY-134321
    8-Azido-cAMP
    8-Azido-cAMP is a fluorescent cAMP analog, acting as the model target of detecting cAMP. 8-Azido-cAMP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    8-Azido-cAMP
  • HY-D3047C
    Rhodamine B-Dextran chloride (MW 20000)
    Rhodamine B-Dextran (MW 20000) is a Rhodamine B (HY-Y0016)-labeled dextran with a molecular weight of 20,000. Rhodamine B-Chitosan (MW 20000) plays an important role in fluorescent labeling, cell imaging, vascular imaging, and drug delivery research (Ex/Em = 546/610 nm).
    Rhodamine B-Dextran chloride (MW 20000)
  • HY-DY1068
    Cyanine5 DBCO hexafluorophosphate (solution)
    Cyanine5 DBCO (DBCO-Cy5) hexafluorophosphate (solution) is a low-toxicity azide reactive probe (NIR fluorescent dye) , for imaging azide-labeled biomolecules via a copper-free "click-through" reaction. Cyanine5 DBCO hexafluorophosphate has no apparent cytotoxicity or animal toxicity and shows no damage to the physiological functions of cells other than the target cells (azide-labeled cells). Cyanine5 DBCO hexafluorophosphate can be used to label and track cells in vitro and in vivo (Ex=635 nm, Em=650-700 nm) .
    Solvent and concentration: DMSO: 10 mM
    Cyanine5 DBCO hexafluorophosphate (solution)
  • HY-D2960
    BC-OG
    BC-OG is an oregon green labeled CLIP tag fluorescent probe. BC-OG can be used for labeling CLIP-tag fusion protein in cells.
    BC-OG
  • HY-161491
    1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA
    1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    1-(2-Aminoethyl)-1H-pyrazol-4-ylphosphonic acid-linker/OVA
  • HY-DY1065
    CY7 (solution)
    CY7 (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Solvent and concentration: DMSO: 10 mM
    CY7 (solution)
  • HY-D3191
    L&M-D-MR
    L&M-D-MR is a highly specific fluorescent "AND" logic probe with response moieties for leucine aminopeptidase (LAP) and monoamine oxidase (MAO). The coexistence of both LAP and MAO is required for L&M-D-MR to trigger intramolecular cyclization, release fluorophores and activate fluorescence. In the presence of only a single enzyme, L&M-D-MR generates only an extremely weak signal. L&M-D-MR enables bioimaging in living cells and mouse models, and can effectively distinguish different subtypes of liver diseases via blood samples or test strips. L&M-D-MR is widely used in studies related to liver cirrhosis, hepatitis B and drug-induced liver injury.
    L&M-D-MR
  • HY-D0235
    Alizarin yellow GG
    Alizarin yellow GG is a dye that exhibits corrosion inhibition effects on mild steel against concentrated H2SO4.
    Alizarin yellow GG
  • HY-D3260
    PerCP-Cy5.5
    PerCP-Cy5.5 is a tandem fluorescent dye composed of a polydinoflavin-chlorophyll protein complex (PerCP) coupled with the anthocyanin dye Cy5.5. PerCP-Cy5.5 is widely used in multicolor flow cytometry analysis (Ex/Em = 48/677-695 nm).
    PerCP-Cy5.5
  • HY-N16328
    Cyanine 7.5 maleimide chloride
    Cy7.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance.
    Cyanine 7.5 maleimide chloride
  • HY-D2845A
    4-arm-PEG5000-FITC
    4-Arm-PEG5000-FITC is a fluorescent dye composed of polyethylene glycol (PEG) and 4 FITC (HY-66019) groups. 4-Arm-PEG5000-FITC can be used for fluorescent labeling and imaging.
    4-arm-PEG5000-FITC
Cat. No. Product Name / Synonyms Application Reactivity