Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10875):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0594S

Iohexol-d₅		99.97%
Iohexol-d₅ is deuterium labeled Iohexol. Iohexol is a radiographic contrast agent and can be applied for myelography, computerized tomography?(cisternography, ventriculography) and MicroCT imaging in vivo.

HY-N0623S7

L-Tryptophan-¹⁵N		99.50%
L-Tryptophan-¹⁵N is the ¹⁵N-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].

HY-N0322S2

Cholesterol-d₆-1		99.82%
Cholesterol-d₆-1 is the deuterium labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist.

HY-N0215S5

L-Phenylalanine-¹⁵N		98.38%
L-Phenylalanine-¹⁵N is the ¹⁵N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a K_i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals.

HY-W021448S

Glycocyamine-d₂		99.90%
Glycocyamine-d₂ (Guanidinoacetic acid-d₂) is the deuterium labeled Glycocyamine (HY-W021448). Glycocyamine is a direct precursor of creatine and an orally active energy metabolism regulator and myogenic differentiation inducer. Glycocyamine can activate the Akt/mTOR/S6K signaling pathway via miR-133a-3p and miR-1a-3p, and stimulate the mRNA expression of myogenic differentiation factor 1 (MyoD) and myopoietin (MyoG). Glycocyamine can increase muscle creatine concentration and maintain ATP homeostasis through the creatine phosphate/creatine kinase system. Glycocyamine can be used in research on feed additives for poultry farming.

HY-N0623S3

L-Tryptophan-1-¹³C		99.94%
L-Tryptophan-1-¹³C is the ¹³C-labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.

HY-32735S

Triptolide-d₃
Triptolide-d₃ is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor.

HY-B2227BS1

Lactate-d₃ sodium (60% w/w in water)		98%
Lactic acid-d₃ (DL-Lactic acid-d₃) sodium (60% in water) is the deuterium labeled Lactic acid sodium (60% in water) (HY-B2227B) . Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity. Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative.

HY-Y0682S

Ethylenediaminetetraacetic acid-d₁₂		99.98%
Ethylenediaminetetraacetic acid-d₁₂ is the deuterium labeled Ethylenediaminetetraacetic acid. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds.

HY-100441S2

Treprostinil-d₉		99.79%
Treprostinil-d₉ (UT-15-d₉) is the deuterium-labeled Treprostinil (HY-100441). Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC₅₀ values of 0.6±0.1 and 6.2±1.2 nM, respectively.

HY-W020005

2-Carboxyphenol-d₄		99.83%
2-Carboxyphenol-d4 is the deuterium labeled 2-Carboxyphenol. 2-Carboxyphenol is a plant hormone and mediates host responses against microbial pathogens.

HY-Y1069S3

(S)-Malic acid-¹³C₄		98.2%
(S)-Malic acid-¹³C₄ is the ¹³C labeled S-Malic acid (HY-Y1069).

HY-N1981S1

Triolein-d₅
Triolein-d₅ is the deuterium labeled Triolein. Triolein is a symmetrical triacylglycerol, reduces MMP-1 upregulation, with strong antioxidant and anti-inflammatory properties.

HY-141923S

Pyridoxamine-d₃ dihydrochloride		99.33%
Pyridoxamine-d₃ (dihydrochloride) is the deuterium labeled Pyridoxamine dihydrochloride.

HY-18569S4

3-Indoleacetic acid-¹³C₆		99.9%
3-Indoleacetic acid-¹³C₆ is the ¹³C labeled 3-Indoleacetic acid (HY-18569). 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

HY-W654342

Spermine-d₂₀		98.47%
Spermine-d₂₀ (NSC 268508-d₂₀) is deuterium labeled Spermine. Spermine (NSC 268508) functions directly as a free radical scabenger to protect DNA from free radical attack. Spermine has antiviral effects.

HY-146726S

Tripentadecanoin-d₂₉		99.24%
Tripentadecanoin-d₂₉ is the deuterium labeled Tripentadecanoin.

HY-N1132S

D-(+)-Trehalose-d₁₄		99.90%
D-(+)-Trehalose-d₁₄ is the deuterium labeled D-(+)-Trehalose. D-(+)-Trehalose, isolated from Saccharomyces cerevisiae, can be used as a food ingredient and pharmaceutical excipi.

HY-146995S

Glycolaldehyde-1-¹³C		99.0%
Glycolaldehyde-1-¹³C is the ¹³C labeled Glycolaldehyde.

HY-W004260S1

Arachidic acid-d₃₉		99.95%
Arachidic acid-d₃₉ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research.

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