Trimethylammonium chloride
Based on 1 Customer Validation
Trimethylammonium chloride (Hegzadesil) is a non-competitive Acetylcholinesterase inhibitor. Trimethylammonium chloride reversibly blocks the deacetylation of acetylcholinesterase.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 593-81-7
- Formula: C3H10ClN
- Molecular Weight:95.57
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Storage:
RT, stored under nitrogen, away from moisture.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Endogenous Metabolite Isoforms
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Biological Activity
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AChE |
Trimethylammonium chloride (75 min) acts as a non-competitive inhibitor of bovine erythrocyte acetylcholinesterase[1].
Trimethylammonium chloride can reversibly block the deacetylation of acetyltransferases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 593-81-7
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Appearance Solid
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Molecular Weight 95.57
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Formula C3H10ClN
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Color Colorless to off-white
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SMILES
CN(C)C.[H]Cl
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Synonyms
Hegzadesil; Trimethylamine hydrochloric acid; Trimethylamine monohydrochloride
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, stored under nitrogen, away from moisture
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 200 mg/mL (2092.71 mM; Need ultrasonic)
DMSO : 41.67 mg/mL (436.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 10.4635 mL | 52.3177 mL | 104.6353 mL | 261.5884 mL |
| 5 mM | 2.0927 mL | 10.4635 mL | 20.9271 mL | 52.3177 mL | |
| 10 mM | 1.0464 mL | 5.2318 mL | 10.4635 mL | 26.1588 mL | |
| 15 mM | 0.6976 mL | 3.4878 mL | 6.9757 mL | 17.4392 mL | |
| 20 mM | 0.5232 mL | 2.6159 mL | 5.2318 mL | 13.0794 mL | |
| 25 mM | 0.4185 mL | 2.0927 mL | 4.1854 mL | 10.4635 mL | |
| 30 mM | 0.3488 mL | 1.7439 mL | 3.4878 mL | 8.7196 mL | |
| 40 mM | 0.2616 mL | 1.3079 mL | 2.6159 mL | 6.5397 mL | |
| 50 mM | 0.2093 mL | 1.0464 mL | 2.0927 mL | 5.2318 mL | |
| 60 mM | 0.1744 mL | 0.8720 mL | 1.7439 mL | 4.3598 mL | |
| 80 mM | 0.1308 mL | 0.6540 mL | 1.3079 mL | 3.2699 mL | |
| 100 mM | 0.1046 mL | 0.5232 mL | 1.0464 mL | 2.6159 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Trimethylammonium chloride Related Classifications
HY-Y0504 Related Classifications
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- Trimethylammonium
- 593-81-7
- Hegzadesil
- Trimethylamine hydrochloric acid
- Trimethylamine monohydrochloride
- Environmental Pollutants
- Endogenous Metabolite
- Cholinesterase (ChE)
- anionic site
- acetylcholinesterase
- enzyme-substrate complex
- bovine erythrocyte acetylcholinesterase
- acetyl enzyme intermediate
- Inhibitor
- inhibitor
- inhibit