2. Trimethylammonium chloride

Trimethylammonium chloride  (Synonyms: Hegzadesil; Trimethylamine hydrochloric acid; Trimethylamine monohydrochloride)

Cat. No.: HY-Y0504 Purity: ≥98.0%
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Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase.

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Trimethylammonium chloride Chemical Structure

Trimethylammonium chloride Chemical Structure

CAS No. : 593-81-7

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10 mM * 1 mL in DMSO
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Description

Trimethylammonium chlorideIt is an endogenous metabolite that inhibits deacetylation. Trimethylammonium chlorideIs a non-competitive inhibitor of acetylcholinesterase[1][2].

Molecular Weight

95.57

Formula

C3H10ClN
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)C.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (436.02 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 10.4635 mL 52.3177 mL 104.6353 mL
5 mM 2.0927 mL 10.4635 mL 20.9271 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 10.4635 mL 52.3177 mL 104.6353 mL 261.5884 mL
5 mM 2.0927 mL 10.4635 mL 20.9271 mL 52.3177 mL
10 mM 1.0464 mL 5.2318 mL 10.4635 mL 26.1588 mL
15 mM 0.6976 mL 3.4878 mL 6.9757 mL 17.4392 mL
20 mM 0.5232 mL 2.6159 mL 5.2318 mL 13.0794 mL
25 mM 0.4185 mL 2.0927 mL 4.1854 mL 10.4635 mL
30 mM 0.3488 mL 1.7439 mL 3.4878 mL 8.7196 mL
40 mM 0.2616 mL 1.3079 mL 2.6159 mL 6.5397 mL
50 mM 0.2093 mL 1.0464 mL 2.0927 mL 5.2318 mL
60 mM 0.1744 mL 0.8720 mL 1.7439 mL 4.3598 mL
80 mM 0.1308 mL 0.6540 mL 1.3079 mL 3.2699 mL
100 mM 0.1046 mL 0.5232 mL 1.0464 mL 2.6159 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trimethylammonium593-81-7Hegzadesil Trimethylamine hydrochloric acid Trimethylamine monohydrochlorideInhibitorinhibitorinhibit

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