2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-141903S
    Taurocholic acid-3-o-glucuronide-d4
    Taurocholic acid-3-o-glucuronide-d4 is the deuterium labeled Taurocholic acid-3-o-glucuronide.
    Taurocholic acid-3-o-glucuronide-d<sub>4</sub>
  • HY-141854S
    2-Butanone 2,4-dinitrophenylhydrazone-d3
    		99.0%
    2-Butanone 2,4-dinitrophenylhydrazone-d3 is the deuterium labeled 2-Butanone 2,4-dinitrophenylhydrazone.
    2-Butanone 2,4-dinitrophenylhydrazone-d<sub>3</sub>
  • HY-175996S
    2-Methyl-5-(p-tolyldiazenyl)aniline-d6
    2-Methyl-5-(p-tolyldiazenyl)aniline-d6 (o-Toluene-azo-o-toluidine-d6) is the deuterium labeled 2-Methyl-5-(p-tolyldiazenyl)aniline (HY-W040297). 2-Methyl-5-(p-tolyldiazenyl)aniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2-Methyl-5-(p-tolyldiazenyl)aniline-d<sub>6</sub>
  • HY-144192S
    MCPA methyl ester-d3
    MCPA methyl ester-d3 is the deuterium labeled MCPA methyl ester.
    MCPA methyl ester-d<sub>3</sub>
  • HY-156209S
    Gb3(d18:1/16:0)-d9
    Gb3(d18:1/16:0)-d9 is deuterium labeled Gb3(d18:1/16:0) (HY-156209). Gb3 (d18:1/16:0) (Compound 1) is the Pk antigen of the P blood group system. Gb3 (d18:1/16:0) acts as a cell surface receptor. Gb3 (d18:1/16:0) is used for research on Burkitt's lymphoma, teratocarcinoma, embryonal carcinoma, and Fabry's disease.
    Gb3(d18:1/16:0)-d<sub>9</sub>
  • HY-142751S
    Fenthion sulfone-d6
    Fenthion sulfone-d6 is the deuterium labeled Fenthion sulfone.
    Fenthion sulfone-d<sub>6</sub>
  • HY-143712S1
    Allolithocholic Acid-d4
    Allolithocholic Acid-d4 (3α-hydoxy-5α-Cholaoic Acid-d4, allo-LCA-d4) is deuterium labeled Allolithocholic acid (HY-143712). Allolithocholic acid is an orally active metabolite of Lithocholic acid (HY-B0172). Allolithocholic acid is a dual GPBAR1 agonist (EC50 = 2.7 μM) and RORγt inverse agonist (IC50 = 3.4 μM). Allolithocholic acid modulates immune and metabolic pathways, regulates immune cell polarization, prevents M1 macrophage and Th17 CD4 cell polarization. Allolithocholic acid improves insulin sensitivity, reduces liver lipid accumulation, reverses liver immunological, inflammatory and metabolic signaling dysregulation, restores bile acid homeostasis, adipose tissue histopathology/function, and intestinal microbiota composition, modulates intestinal immunity. Allolithocholic acid can be used for the researches of cancer, inflammayion, immunology and metabolic disease.
    Allolithocholic Acid-d<sub>4</sub>
  • HY-114456AS
    Ganglioside GM3-d5 Bovine Milk ammonium salt
    Ganglioside GM3-d5 (Bovine Milk ammonium salt) is deuterium labeled Ganglioside GM3 (Bovine Milk ammonium salt).
    Ganglioside GM3-d<sub>5</sub> Bovine Milk ammonium salt
  • HY-W007720S1
    Fmoc-Ser-OH-15N
    		98.0%
    Fmoc-Ser-OH-15N is the 15N labeled Fmoc-Ser-OH.
    Fmoc-Ser-OH-<sup>15</sup>N
  • HY-10846S1
    Delamanid-d4-1
    Delamanid-d4-1 is deuterated labeled Delamanid.Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids.
    Delamanid-d<sub>4</sub>-1
  • HY-109541S1
    Colfosceril miristate-d4
    Colfosceril miristate-d4 (DMPC-d4) is deuterium labeled Colfosceril miristate. Colfosceril miristate is a synthetic phospholipid used in liposomes. Colfosceril miristate is used to study lipid monolayers, bilayers and drug delivery.
    Colfosceril miristate-d<sub>4</sub>
  • HY-W740013
    N-Depropyl propafenone-d5 oxalate salt
    N-Depropyl propafenone-d5 (oxalate salt) is the deuterium labeled 1-Propanone, 1-[2-(3-amino-2-hydroxypropoxy)phenyl]-3-phenyl-, ethanedioate (1:1) (HY-W587538).
    N-Depropyl propafenone-d<sub>5</sub> oxalate salt
  • HY-10805S
    Almorexant-13C,d3
    Almorexant-13C,d3 is the 13C- and deuterium labeled Almorexant. Almorexant (ACT 078573) is a potent and competitive dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist with Ki values of 1.3 and 0.17 nM, respectively.
    Almorexant-<sup>13</sup>C,d<sub>3</sub>
  • HY-W707578
    (2R)-Sorbitan Monolauric Acid Ester-d22
    (2R)-Sorbitan Monolauric Acid Ester-d22-1 is the deuterium labeled (2R)-Sorbitan Monolauric Acid Ester.
    (2R)-Sorbitan Monolauric Acid Ester-d<sub>22</sub>
  • HY-W777751
    6-Desamino 6-chloro etravirine-13C3
    6-Desamino 6-chloro etravirine-13C3 is the 13C-labeled 6-Desamino 6-Chloro Etravirine (HY-W740641).
    6-Desamino 6-chloro etravirine-<sup>13</sup>C<sub>3</sub>
  • HY-141617S1
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d31 is the deuterium labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE (HY-141617). 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control.
    1-Palmitoyl-2-hydroxy-sn-glycero-3-PE-d<sub>31</sub>
  • HY-N0325S
    DL-Methionine-13C
    DL-Methionine-13C is the 13C-labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants.
    DL-Methionine-<sup>13</sup>C
  • HY-W768895
    Sanguinarine chloride-13C,d3
    Sanguinarine chloride-13C,d3 (Sanguinarin chloride-13C,d3) is the deuterium labeled Sanguinarine chloride (HY-N0052A). Sanguinarine (Sanguinarin) chloride, a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
    Sanguinarine chloride-<sup>13</sup>C,d<sub>3</sub>
  • HY-113308S
    Taurolithocholic acid-d5
    Taurolithocholic acid-d5 is deuterium labeled Taurolithocholic acid. Taurolithocholic acid is an orally active bile acid and antiviral agent. Taurolithocholic acid upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis.
    Taurolithocholic acid-d<sub>5</sub>
  • HY-10844S1
    Pretomanid-d5
    Pretomanid-d5 is deuterated labeled Pretomanid (HY-10844). Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL.
    Pretomanid-d<sub>5</sub>