2. Signaling Pathways
  3. Others
  4. mRNA

mRNA

messenger RNA

 

mRNA Related Products (325):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174495
    Human EPO mRNA
    Human EPO mRNA encodes the human erythropoietin (EPO) protein, a hormone that controls erythropoiesis, or red blood cell production. EPO also plays a role in wound healing and the brain’s response to neural injury. Kariko et al. showed that transfection of EPO mRNA in vivo resulted in significant increases of both reticulocyte counts and hematocrits.
    Human EPO mRNA
  • HY-174678
    Human FOXA3 mRNA
    Human FOXA3 mRNA encodes the human forkhead box A3 (FOXA3) protein which is thought to act as a ''pioneer'' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.
    Human FOXA3 mRNA
  • HY-174703
    Human FGF19 mRNA
    Human FGF19 mRNA encodes the human fibroblast growth factor 19 (FGF19) protein, a member of the fibroblast growth factor (FGF) family. FGF19 probably involves in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades.
    Human FGF19 mRNA
  • HY-174732
    Human CSF3 mRNA
    Human CSF3 mRNA encodes the human colony stimulating factor 3 (CSF3) protein, a member of the IL-6 superfamily of cytokines. CSF3 controls the production, differentiation, and function of granulocytes.
    Human CSF3 mRNA
  • HY-174689
    Human FGFR2 mRNA
    Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.
    Human FGFR2 mRNA
  • HY-174551
    Human PDGFC mRNA
    Human PDGFC mRNA encodes the human platelet derived growth factor C (PDGFC) protein, a member of the platelet-derived growth factor family. PDGFC plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFC mRNA
  • HY-174629
    Human IL19 mRNA
    Human IL19 mRNA encodes the human interleukin 19 (IL19) protein, a cytokine that belongs to the IL10 cytokine subfamily. IL19 may play some important roles in inflammatory responses.
    Human IL19 mRNA
  • HY-174595
    Human IL9R mRNA
    Human IL9R mRNA encodes the human interleukin 9 receptor (IL9R) protein, a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9).
    Human IL9R mRNA
  • HY-174707
    Human FGF14 mRNA
    Human FGF14 mRNA encodes the human fibroblast growth factor 14 (FGF14) protein, a member of the fibroblast growth factor (FGF) family. FGF14 probably involves in nervous system development and function.
    Human FGF14 mRNA
  • HY-174628
    Human IL1A mRNA
    Human IL1A mRNA encodes the human interleukin 1 alpha (IL1A) protein, a member of the interleukin 1 cytokine family. IL1A is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis.
    Human IL1A mRNA
  • HY-174606
    Human IL34 mRNA
    Human IL34 mRNA encodes the human interleukin 34 (IL34) protein, a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R).
    Human IL34 mRNA
  • HY-174767
    Human CCL16 mRNA
    Human CCL16 mRNA encodes the human C-C motif chemokine ligand 16 (CCL16) protein, a cytokine that displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. CCL16 also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells.
    Human CCL16 mRNA
  • HY-174778
    Human ASCL1 mRNA
    Human ASCL1 mRNA encodes the human achaete-scute family bHLH transcription factor 1 (ASCL1) protein, a member of the basic helix-loop-helix (BHLH) family. ASCL1 plays a role in the neuronal commitment and differentiation, and in the generation of olfactory and autonomic neurons.
    Human ASCL1 mRNA
  • HY-174568
    Human NFKB2 mRNA
    Human NFKB2 mRNA encodes the human nuclear factor kappa B subunit 2 (NFKB2) protein, a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. NFKB2 can function as either a transcriptional activator or repressor depending on its dimerization partner.
    Human NFKB2 mRNA
  • HY-174553
    Human PDGFA mRNA
    Human PDGFA mRNA encodes the human platelet derived growth factor A (PDGFA) protein, a member of the platelet-derived growth factor family. PDGFA plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
    Human PDGFA mRNA
  • HY-183851
    KKL-55
    		Inhibitor
    KKL-55 is a broad-spectrum antibacterial agent that inhibits the trans-translation pathway and the ClpXP protease. KKL-55 suppresses trans-translation of non-stop mRNA, interferes with the binding of EF-Tu to tmRNA, and inhibits the proteolysis of substrates by ClpXP. KKL-55 blocks spore germination of Bacillus anthracis and protects macrophages from damage induced by anthrax toxin. By virtue of its inhibitory effect on ClpXP, KKL-55 synergistically enhances the antibacterial activity of antibiotics against drug-resistant Staphylococcus aureus. KKL-55 can be used in studies related to bacterial infections.
    KKL-55
  • HY-174766
    Human CCL17 mRNA
    Human CCL17 mRNA encodes the human C-C motif chemokine ligand 17 (CCL17) protein, a cytokine that displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
    Human CCL17 mRNA
  • HY-174755
    Human CCL27 mRNA
    Human CCL27 mRNA encodes the human C-C motif chemokine ligand 27 (CCL27) protein, a chemotactic for skin-associated memory T lymphocytes. CCL27 also plays a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10).
    Human CCL27 mRNA
  • HY-174693
    Human FGF7 mRNA
    Human FGF7 mRNA encodes the human fibroblast growth factor 7 (FGF7) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
    Human FGF7 mRNA
  • HY-174768
    Human CCL15 mRNA
    Human CCL15 mRNA encodes the human C-C motif chemokine ligand 15 (CCL15) protein, a chemotactic for T cells and monocytes, and acts through C-C chemokine receptor type 1 (CCR1).
    Human CCL15 mRNA