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Reference Standards
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Reference Standards Related Products (11524)
Related Products (11524)
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Murrayafoline A (Standard)
0 ImagesCat. No.: HY-W100287RCAS No.: 4532-33-6Murrayafoline A (Standard) is the analytical standard of Murrayafoline A (HY-W100287). This product is intended for research and analytical applications. Murrayafoline A is a carbazole alkaloid that can be extracted from Murraya tetramera. Murrayafoline A directly targets Specificity protein 1 (Sp1), thereby inhibiting NF-κB and MAPK signaling pathways. Murrayafoline a induces a G0/G1-phase arrest in platelet-derived growth factor (PDGF)-stimulated vascular smooth muscle cells. Murrayafoline A attenuates the Wnt/β-catenin pathway by promoting the degradation of intracellular β-catenin proteins. Murrayafoline A enhances the contraction of rat ventricular myocytes and L-type calcium current by activating protein kinase C. Murrayafoline A inhibits LPS (HY-D1056)-induced neuroinflammation in vivo. Murrayafoline A can be used for the study of inflammation, vascular complications and colon cancer. -
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GSK1059865 (Standard)
0 ImagesCat. No.: HY-101534RCAS No.: 1191044-58-2GSK1059865 (Standard) is the analytical standard of GSK1059865 (HY-101534). This product is intended for research and analytical applications. GSK1059865 is a potent orexin 1 receptor antagonist. -
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Idazoxan hydrochloride (Standard)
0 ImagesCat. No.: HY-14561ARCAS No.: 79944-56-2Synonyms: RX 781094 hydrochloride (Standard)Idazoxan (hydrochloride) (Standard) is the analytical standard of Idazoxan (hydrochloride). This product is intended for research and analytical applications. Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism. -
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SDZ-MKS 492 (Standard)
0 ImagesCat. No.: HY-100164RCAS No.: 114606-56-3Synonyms: MKS 492 (Standard)SDZ-MKS 492 (Standard) is the analytical standard of SDZ-MKS 492 (HY-100164). This product is intended for research and analytical applications. SDZ-MKS 492 (MKS 492) is a selective inhibitor of cyclic GMP-inhibited phosphodiesterase (type III PDE). SDZ-MKS 492 inhibits antigen- or platelet activating factor (PAF)-induced bronchoconstriction and allergic reactions in guinea pigs and rats. -
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3-Methylsalicylic acid (Standard)
0 ImagesSynonyms: o-Cresotic acid (Standard); Hydroxytoluic acid (Standard)3-Methylsalicylic acid (Standard) is the analytical standard of 3-Methylsalicylic acid. This product is intended for research and analytical applications. 3-Methylsalicylic acid (o-Cresotic acid) is a derivative of salicylic acid. 3-Methylsalicylic acid exhibits significant fibrinolytic activity in human plasma by activating the fibrinolytic system. 3-Methylsalicylic acid can be used as an intermediate for the synthesis of other compounds. 3-Methylsalicylic acid inhibits the feeding of midges. -
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Ticagrelor impurity 12 (Standard)
0 ImagesCat. No.: HY-78540RCAS No.: 220241-61-2Ticagrelor impurity 12 (Standard) is the analytical standard of Ticagrelor impurity 12 (HY-78540). This product is intended for research and analytical applications. -
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Phthaloylamlodipine (Standard)
0 ImagesCat. No.: HY-137163RCAS No.: 88150-62-3Synonyms: Phthaloyl Amlodipine (Standard)Phthaloylamlodipine (Standard) is the analytical standard of Phthaloylamlodipine. This product is intended for research and analytical applications. -
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YM-58790 (Standard)
0 ImagesCat. No.: HY-101679RCAS No.: 214558-72-2YM-58790 (Standard) is the analytical standard of YM-58790 (HY-101679). This product is intended for research and analytical applications. YM-58790 is a potent antagonist of mAChR. YM-58790 binds M1, M2, M3 with Ki values of 28 nM, 260 nM, and 15 nM. YM-58790 exhibits potent inhibitory activity on bladder pressuer in reflexly-evoked rhythmic contraction in rats. -
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Itacnosertib hydrochloride (Standard)
0 ImagesCat. No.: HY-109179ARCAS No.: 2409543-84-4Synonyms: TP-0184 hydrochloride (Standard)Itacnosertib hydrochloride (Standard) is the analytical standard of Itacnosertib (hydrochloride) (HY-109179A). This product is intended for research and analytical applications. Itacnosertib hydrochloride (TP-0184 hydrochloride) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib hydrochloride exhibits anti-leukemic activity. -
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Cinaciguat (Standard)
0 ImagesCat. No.: HY-14181RCAS No.: 329773-35-5Synonyms: BAY 58-2667 (Standard)Cinaciguat (Standard) is the analytical standard of Cinaciguat. This product is intended for research and analytical applications. Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. -
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DHBP dibromide (Standard)
0 ImagesSynonyms: Diheptylviologen dibromide (Standard)DHBP (dibromide) (Standard) is the analytical standard of DHBP (dibromide) (HY-101237). This product is intended for research and analytical applications. DHBP dibromide is an inhibitor for calcium release and a muscle relaxant. -
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AEG3482 (Standard)
0 ImagesCat. No.: HY-107599RCAS No.: 63735-71-7AEG3482 (Standard) is the analytical standard of AEG3482 (HY-107599). This product is intended for research and analytical applications. AEG3482 is a potent antiapoptotic compound that inhibits Jun Kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25. -
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Eliprodil (Standard)
0 ImagesSynonyms: SL-820715 (Standard)Eliprodil (Standard) is the analytical standard of Eliprodil. This product is intended for research and analytical applications. 0 -
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Chlorfenson (Standard)
0 ImagesCat. No.: HY-121157RCAS No.: 80-33-1Chlorfenson (Standard) is the analytical standard of Chlorfenson. This product is intended for research and analytical applications. Chlorfenson is an acaricide. -
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3-(3-Methoxyphenyl)propionic acid (Standard)
0 ImagesCat. No.: HY-W016482RCAS No.: 10516-71-93-(3-Methoxyphenyl)propionic acid (Standard) is the analytical standard of 3-(3-Methoxyphenyl)propionic acid (HY-W016482). This product is intended for research and analytical applications. 3-(3-Methoxyphenyl) propionic acid is an organic acid and endogenous metabolite. 3-(3-Methoxyphenyl) propionic acid is excreted in urine. -
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ZAPA sulfate (Standard)
0 ImagesZAPA (sulfate) (Standard) is the analytical standard of ZAPA (sulfate) (HY-100799). This product is intended for research and analytical applications. ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM. -
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Ivacaftor (Standard)
0 ImagesSynonyms: VX-770 (Standard)Ivacaftor (Standard) is the analytical standard of Ivacaftor. This product is intended for research and analytical applications. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively. -
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RA190 (Standard)
0 ImagesCat. No.: HY-100739RCAS No.: 1617495-03-0RA190 (Standard) is the analytical standard of RA190 (HY-100739). This product is intended for research and analytical applications. RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. -
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Zonisamide (Standard)
0 ImagesSynonyms: AD 810 (Standard); CI 912 (Standard)Zonisamide (Standard) is the analytical standard of Zonisamide. This product is intended for research and analytical applications. Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with Kis of 35.2 and 20.6 nM for hCA II and hCA V, respectively. Zonisamide exerts neuroprotective effects through anti-apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1, thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinson’s disease and cardiac hypertrophy. -
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BAY-218 (Standard)
0 ImagesCat. No.: HY-111449RCAS No.: 2162982-11-6Synonyms: AHR antagonist 1 (Standard)BAY-218 (Standard) is the analytical standard of BAY-218 (HY-111449). This product is intended for research and analytical applications. BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses. -
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