119431-25-3
119431-25-3
Chemical Structure
Eliprodil
Synonym(s): SL-820715
- CAS No.: 119431-25-3
- Formula:C20H23ClFNO
- Molecular Weight:347.85
IUPAC Name: 1-(4-chlorophenyl)-2-(4-(4-fluorobenzyl)piperidin-1-yl)ethan-1-ol
InChIKey: GGUSQTSTQSHJAH-UHFFFAOYSA-N
SMILES: ClC(C=C1)=CC=C1C(O)CN(CC2)CCC2CC3=CC=C(F)C=C3
Biological Activity:
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Eliprodil | 99.65% | Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). | ||||||||||||||||||||
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Eliprodil (Standard) | ≥98% | Eliprodil (Standard) is the analytical standard of Eliprodil. This product is intended for research and analytical applications. 0 | ||||||||||||||||||||
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References
- Bath CP, et al. The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12. [Content Brief]
- Lengyel C, et al. Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk. Br J Pharmacol. 2004 Sep;143(1):152-8. [Content Brief]
