1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. DHBP dibromide

DHBP dibromide (Synonyms: Diheptylviologen dibromide)

Cat. No.: HY-101237 Purity: 99.97%
Handling Instructions

DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

For research use only. We do not sell to patients.

DHBP dibromide Chemical Structure

DHBP dibromide Chemical Structure

CAS No. : 6159-05-3

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10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
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ready for reconstitution
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Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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DHBP dibromide is an inhibitor for calcium release and a muscle relaxant.

In Vitro

DHBP inhibits the calcium release induced by 2 mM caffeine and 2 μg/mL polylysine with an IC50 value of 5 μg/mL and 4 μg/mL, respectively. DHBP inhibits [3H]-ryanodine binding in a dose-dependent manner with an IC50 of 2.5 μg/mL and 90-100% inhibition at 20-30 μg/mL. Calcium uptake by SR is inhibited in the presence of caffeine and this inhibition is antagonized by concomitant addition of DHBP. Muscle twitches elicited by direct electrical muscle stimulation and contractions induced by either 10 mM caffeine or 1 fLM ryanodine are blocked by pretreatment with DHBP. DHBP blocks the calcium release from SR by direct interaction with the calcium release channel, also known as the ryanodine receptor[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight





Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (194.41 mM; Need ultrasonic)

DMSO : ≥ 30 mg/mL (58.32 mM)

*"≥" means soluble, but saturation unknown.

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9441 mL 9.7204 mL 19.4409 mL
5 mM 0.3888 mL 1.9441 mL 3.8882 mL
10 mM 0.1944 mL 0.9720 mL 1.9441 mL
*Please refer to the solubility information to select the appropriate solvent.
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