GSK1059865 (Standard)
GSK1059865 (Standard) is the analytical standard of GSK1059865 (HY-101534). This product is intended for research and analytical applications. GSK1059865 is a potent orexin 1 receptor antagonist.
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- CAS No.: 1191044-58-2
- Formule: C20H23BrFN3O2
- Masse moléculaire:436.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-100452
TCS-OX2-29OX2R Antagonist -
HY-101534
GSK1059865OX1 Antagonist -
HY-15653
FilorexantOX Receptor Antagonist -
HY-10898
SB-674042OX1 Receptor Antagonist -
HY-19320
Orexin 2 Receptor AgonistOX2R Agonist -
HY-19914
MK-1064OX2R Antagonist -
HY-10900
TCS 1102OX Receptor Antagonist -
HY-10895
SB-334867OX1 Receptor Antagonist -
HY-13796
IPSU -
HY-12301
MK-3697OX2R Antagonist -
HY-10896
JNJ-10397049OX2R Antagonist -
HY-109012
SeltorexantOrexin-2 Receptor Antagonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1191044-58-2
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Masse moléculaire 436.32
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Formule C20H23BrFN3O2
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SMILES
O=C(N1[C@H](CNC2=NC=C(Br)C=C2)CC[C@H](C)C1)C3=CC=CC(F)=C3OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Lopez MF, et al. The highly selective orexin/hypocretin 1 receptor antagonist GSK1059865 potently reduces ethanol drinking in ethanol dependent mice. Brain Res. 2016 Apr 1;1636:74-80. [Content Brief]
[2]. Piccoli L, et al. Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats. Neuropsychopharmacology. 2012 Aug;37(9):1999-2011. [Content Brief]
[3]. Gozzi A, et al. Differential effect of orexin-1 and CRF-1 antagonism on stress circuits: a fMRI study in the rat with the pharmacological stressor Yohimbine. Neuropsychopharmacology. 2013 Oct;38(11):2120-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK1059865 (Standard) Related Classifications
HY-101534R Related Classifications
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