2. Others MAPK/ERK Pathway Apoptosis
  3. Reference Standards JNK Apoptosis
  4. AEG3482 (Standard)

AEG3482 (Standard) is the analytical standard of AEG3482 (HY-107599). This product is intended for research and analytical applications. AEG3482 is a potent antiapoptotic compound that inhibits Jun Kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25.

For research use only. We do not sell to patients.

AEG3482 (Standard)

AEG3482 (Standard) Chemical Structure

CAS No. : 63735-71-7

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AEG3482 (Standard) Related Antibodies

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Description

AEG3482 (Standard) is the analytical standard of AEG3482 (HY-107599). This product is intended for research and analytical applications. AEG3482 is a potent antiapoptotic compound that inhibits Jun Kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25[1].

IC50 & Target

JNK[1]
Molecular Weight

280.33

Formula

C10H8N4O2S2
CAS No.
SMILES

O=S(C1=NN2C(S1)=NC(C3=CC=CC=C3)=C2)(N)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AEG3482 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AEG3482 (Standard)63735-71-7Reference StandardsJNKApoptosisc-Jun N-terminal kinaseantiapoptoticJunkinaseheatshockprotein70HSP70HSP90HSF1Inhibitorinhibitorinhibit

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