ZAPA sulfate
Based on 1 Customer Validation
ZAPA sulfate is an agonist at low affinity GABAA-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC50 of 10.3 μM.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 371962-01-5
- Formula: C4H8N2O6S2
- Molecular Weight:244.25
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Local applications of ZAPA (100 μM) sulfate transiently increases [Ca2+]i, similar to the GABA-evoked responses[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 371962-01-5
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Appearance Solid
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Molecular Weight 244.25
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Formula C4H8N2O6S2
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Color White to off-white
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SMILES
O=C(O)/C=C\SC(N)=N.O=S(O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 31.25 mg/mL (127.94 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 1.64 mg/mL (6.71 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 4.0942 mL | 20.4708 mL | 40.9417 mL | 102.3541 mL |
| 5 mM | 0.8188 mL | 4.0942 mL | 8.1883 mL | 20.4708 mL | |
| DMSO | 10 mM | 0.4094 mL | 2.0471 mL | 4.0942 mL | 10.2354 mL |
| 15 mM | 0.2729 mL | 1.3647 mL | 2.7294 mL | 6.8236 mL | |
| 20 mM | 0.2047 mL | 1.0235 mL | 2.0471 mL | 5.1177 mL | |
| 25 mM | 0.1638 mL | 0.8188 mL | 1.6377 mL | 4.0942 mL | |
| 30 mM | 0.1365 mL | 0.6824 mL | 1.3647 mL | 3.4118 mL | |
| 40 mM | 0.1024 mL | 0.5118 mL | 1.0235 mL | 2.5589 mL | |
| 50 mM | 0.0819 mL | 0.4094 mL | 0.8188 mL | 2.0471 mL | |
| 60 mM | 0.0682 mL | 0.3412 mL | 0.6824 mL | 1.7059 mL | |
| 80 mM | 0.0512 mL | 0.2559 mL | 0.5118 mL | 1.2794 mL | |
| 100 mM | 0.0409 mL | 0.2047 mL | 0.4094 mL | 1.0235 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
ZAPA sulfate Related Classifications
HY-100799 Related Classifications
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