SMARCA4 Ligand

(+)-JQ-1 (JQ1), a chemical probe, is a potent, specific, CNS-penetrant and reversible BET bromodomain inhibitor, with IC₅₀s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). (+)-JQ-1 also activates autophagy.

SMARCA2/4-ligand-8 is a SMARCA2/4 ligand, which can be used for the synthesis of PROTACs, such as PROTAC SMARCA2/4-degrader-26 (HY-162815).

SMARCA-BD ligand 1 for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

SMARCA-BD ligand 1 hydrochloride for PROTAC is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

SMARCA-BD ligand 1 for PROTAC dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

SMARCA2/4-ligand-3 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). SMARCA2/4-ligand-3 can be used for synthesis PROTAC SMARCA2/4-degrader-25 (HY-162813).

BRM/BRG1 ligand 2 is the ligand for target protein, which can be used for synthesis of PROTAC BRM/BRG1 degrader-2 (HY-168247).

BRM/BRG1 ligand 3 is a target protein ligand that can be used to synthesize PROTAC BRM/BRG1 degrader-3 (HY-168251).

SMARCA2/4-ligand-6 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). SMARCA2/4-ligand-6 can be used for the synthesis of SMD-3040 (HY-156568).

SMARCA2/4-ligand-4 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). SMARCA2/4-ligand-4 can be used for the synthesis of PROTAC SMARCA2/4 degrader-36 (HY-170347).

BRM/BRG1 ligand 1 is a BRM/BRG1 ligand, and can be used for synthesis of PROTAC BRM/BRG1 degrader-1 (HY-168242).