PROTAC SMARCA2/4 degrader-36
PROTAC SMARCA2/4 degrader-36 (Compound 29) is an effective dual degrader of SMARCA2/4,with DC50 values of 0.22 nM and 0.85 nM for SMARCA2 and SMARCA4, respectively. PROTAC SMARCA2/4 degrader-36 has anti-cell proliferation activity.
(Pink: SMARCA2 and SMARCA4 ligand (HY-170354); Blue: VHL ligand (HY-170353); Black: linker).
For research use only. We do not sell to patients.
- CAS No.: 3033588-00-7
- Formula: C53H62ClN9O4S
- Molecular Weight:956.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 3033588-00-7
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Molecular Weight 956.64
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Formula C53H62ClN9O4S
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SMILES
ClC1=CC=CC(N(C(C=CC(C2CCN(C[C@H]3CC[C@H](C4=CN([C@H](C(N5C[C@H](O)C[C@H]5C(N[C@@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)=O)C(C)C)N=N4)CC3)CC2)=C8)=C8C9(C)C)C9=N%10)=C1C%10=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC SMARCA2/4 degrader-36 Related Classifications
HY-170347 Related Classifications
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