1. PROTAC
  2. Ligands for Target Protein for PROTAC
  3. SMARCA-BD ligand 1 for Protac

SMARCA-BD ligand 1 for Protac is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (SMARCA-BD ligand 1 for Protac hydrochloride and SMARCA-BD ligand 1 for Protac dihydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

SMARCA-BD ligand 1 for Protac Chemical Structure

SMARCA-BD ligand 1 for Protac Chemical Structure

CAS No. : 1997319-92-2

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Description

SMARCA-BD ligand 1 for Protac is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

IC50 & Target

SMARCA2[1]

Molecular Weight

271.32

Formula

C14H17N5O

CAS No.
SMILES

OC1=CC=CC=C1C2=NN=C(N)C(N3CCNCC3)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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SMARCA-BD ligand 1 for Protac Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SMARCA-BD ligand 1 for Protac
Cat. No.:
HY-44012
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