Ac-Cys-Deruxtecan
Based on 1 Customer Validation
Ac-Cys-Deruxtecan is a drug linker intermediate used in antibody-drug conjugate manufacturing.Ac-Cys-Deruxtecan reacts with reduced antibodies, and excess unreacted forms are quenched by thiol-containing reagents.
For research use only. We do not sell to patients.
- CAS No.: 2409510-92-3
- Formula: C57H65FN10O16S
- Molecular Weight:1197.25
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2409510-92-3
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Appearance Solid
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Molecular Weight 1197.25
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Formula C57H65FN10O16S
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Color White to off-white
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SMILES
O=C(C(CC1=O)SC[C@@H](C(O)=O)NC(C)=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (83.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8352 mL | 4.1762 mL | 8.3525 mL | 20.8812 mL |
| 5 mM | 0.1670 mL | 0.8352 mL | 1.6705 mL | 4.1762 mL | |
| 10 mM | 0.0835 mL | 0.4176 mL | 0.8352 mL | 2.0881 mL | |
| 15 mM | 0.0557 mL | 0.2784 mL | 0.5568 mL | 1.3921 mL | |
| 20 mM | 0.0418 mL | 0.2088 mL | 0.4176 mL | 1.0441 mL | |
| 25 mM | 0.0334 mL | 0.1670 mL | 0.3341 mL | 0.8352 mL | |
| 30 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6960 mL | |
| 40 mM | 0.0209 mL | 0.1044 mL | 0.2088 mL | 0.5220 mL | |
| 50 mM | 0.0167 mL | 0.0835 mL | 0.1670 mL | 0.4176 mL | |
| 60 mM | 0.0139 mL | 0.0696 mL | 0.1392 mL | 0.3480 mL | |
| 80 mM | 0.0104 mL | 0.0522 mL | 0.1044 mL | 0.2610 mL |
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