Ac-Cys-Deruxtecan
Ac-Cys-Deruxtecan is a drug linker intermediate used in antibody-drug conjugate manufacturing.Ac-Cys-Deruxtecan reacts with reduced antibodies, and excess unreacted forms are quenched by thiol-containing reagents.
For research use only. We do not sell to patients.
- CAS No.: 2409510-92-3
- Formula: C57H65FN10O16S
- Molecular Weight:1197.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2409510-92-3
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Molecular Weight 1197.25
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Formula C57H65FN10O16S
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SMILES
O=C(C(CC1=O)SC[C@@H](C(O)=O)NC(C)=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : ≥ 100 mg/mL (83.52 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8352 mL | 4.1762 mL | 8.3525 mL | 20.8812 mL |
| 5 mM | 0.1670 mL | 0.8352 mL | 1.6705 mL | 4.1762 mL | |
| 10 mM | 0.0835 mL | 0.4176 mL | 0.8352 mL | 2.0881 mL | |
| 15 mM | 0.0557 mL | 0.2784 mL | 0.5568 mL | 1.3921 mL | |
| 20 mM | 0.0418 mL | 0.2088 mL | 0.4176 mL | 1.0441 mL | |
| 25 mM | 0.0334 mL | 0.1670 mL | 0.3341 mL | 0.8352 mL | |
| 30 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6960 mL | |
| 40 mM | 0.0209 mL | 0.1044 mL | 0.2088 mL | 0.5220 mL | |
| 50 mM | 0.0167 mL | 0.0835 mL | 0.1670 mL | 0.4176 mL | |
| 60 mM | 0.0139 mL | 0.0696 mL | 0.1392 mL | 0.3480 mL | |
| 80 mM | 0.0104 mL | 0.0522 mL | 0.1044 mL | 0.2610 mL |
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