2. Metabolic Enzyme/Protease
  3. PGC-1α
  4. Ac-SVVVRT-NH2

Ac-SVVVRT-NH2 is a PGC-1α modulator that modulates the activity of the human PGC-1α promoter (114%). Ac-SVVVRT-NH2 increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 can be used in the research of diseases which is modulated by PGC-1α.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-SVVVRT-NH2 Chemical Structure

Ac-SVVVRT-NH2 Chemical Structure

CAS No. : 1401804-69-0

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Based on 1 publication(s) in Google Scholar

Ac-SVVVRT-NH2 Related Antibodies

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  • Biological Activity

  • Purity & Documentation

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Description

Ac-SVVVRT-NH2 is a PGC-1α modulator that modulates the activity of the human PGC-1α promoter (114%). Ac-SVVVRT-NH2 increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 can be used in the research of diseases which is modulated by PGC-1α[1].

IC50 & Target

PGC-1α[1]
In Vitro

Ac-SVVVRT-NH2 (Ac-SEQ ID No.2-NH2, 0.1 mg/mL, 10 days) increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes[1].
Ac-SVVVRT-NH2 (0.5 mg/mL, 24 h) modulates the activity of the human PGC-1α promoter (114%) in HepG2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ac-SVVVRT-NH2 Related Antibodies
Molecular Weight

700.83

Formula

C30H56N10O9
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Ac-SVVVRT-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (71.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4269 mL 7.1344 mL 14.2688 mL
5 mM 0.2854 mL 1.4269 mL 2.8538 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4269 mL 7.1344 mL 14.2688 mL 35.6720 mL
5 mM 0.2854 mL 1.4269 mL 2.8538 mL 7.1344 mL
10 mM 0.1427 mL 0.7134 mL 1.4269 mL 3.5672 mL
15 mM 0.0951 mL 0.4756 mL 0.9513 mL 2.3781 mL
20 mM 0.0713 mL 0.3567 mL 0.7134 mL 1.7836 mL
25 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.4269 mL
30 mM 0.0476 mL 0.2378 mL 0.4756 mL 1.1891 mL
40 mM 0.0357 mL 0.1784 mL 0.3567 mL 0.8918 mL
50 mM 0.0285 mL 0.1427 mL 0.2854 mL 0.7134 mL
60 mM 0.0238 mL 0.1189 mL 0.2378 mL 0.5945 mL
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Ac-SVVVRT-NH2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-SVVVRT-NH21401804-69-0PGC-1αPPARγ coactivator-1αLipidadipocytesHepG2Inhibitorinhibitorinhibit

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