Ac-SVVVRT-NH2
Based on 1 Customer Validation
Ac-SVVVRT-NH2 is a PGC-1α modulator that modulates the activity of the human PGC-1α promoter (114%). Ac-SVVVRT-NH2 increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes. Ac-SVVVRT-NH2 can be used in the research of diseases which is modulated by PGC-1α.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.68%
- CAS. Nr.: 1401804-69-0
- Formel: C30H56N10O9
- Molecular Weight:700.83
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Speicherung:
Sealed storage, away from moisture and light, under nitrogen.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
PGC-1α[1]
In Vitro
Ac-SVVVRT-NH2 (Ac-SEQ ID No.2-NH2, 0.1 mg/mL, 10 days) increases PGC-1α mRNA (125%) and accumulation of intracellular lipids (128%) in subcutaneous human adipocytes[1].
Ac-SVVVRT-NH2 (0.5 mg/mL, 24 h) modulates the activity of the human PGC-1α promoter (114%) in HepG2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1401804-69-0
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Appearance Solid
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Molecular Weight 700.83
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Formel C30H56N10O9
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Color White to off-white
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Sequence Shortening
Ac-SVVVRT-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Sealed storage, away from moisture and light, under nitrogen
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 50 mg/mL (71.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.4269 mL | 7.1344 mL | 14.2688 mL | 35.6720 mL |
| 5 mM | 0.2854 mL | 1.4269 mL | 2.8538 mL | 7.1344 mL | |
| 10 mM | 0.1427 mL | 0.7134 mL | 1.4269 mL | 3.5672 mL | |
| 15 mM | 0.0951 mL | 0.4756 mL | 0.9513 mL | 2.3781 mL | |
| 20 mM | 0.0713 mL | 0.3567 mL | 0.7134 mL | 1.7836 mL | |
| 25 mM | 0.0571 mL | 0.2854 mL | 0.5708 mL | 1.4269 mL | |
| 30 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1891 mL | |
| 40 mM | 0.0357 mL | 0.1784 mL | 0.3567 mL | 0.8918 mL | |
| 50 mM | 0.0285 mL | 0.1427 mL | 0.2854 mL | 0.7134 mL | |
| 60 mM | 0.0238 mL | 0.1189 mL | 0.2378 mL | 0.5945 mL |
Ac-SVVVRT-NH2 Related Classifications
HY-P3455 Related Classifications
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