Acetyl hexapeptide-1
Based on 1 Customer Validation
Acetyl hexapeptide-1 (Melitane) is a biomimetic peptide that mimics the activity of α-melanocyte-stimulating hormone (α-MSH). Acetyl hexapeptide-1 regulates muscle contraction, thereby reducing facial expression lines. Acetyl hexapeptide-1 is one of the components of anti-aging skincare serums targeting dynamic wrinkles. Acetyl hexapeptide-1 can be used in research related to mild photoaged facial skin and premature gray hair.
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- Pureza : 99.43%
- No. CAS: 448944-47-6
- Fòrmula: C43H59N13O7
- Peso molecular:870.01
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Almacenamiento:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-W013494
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Palmitoyl Tetrapeptide-3IL-6 Inhibitor -
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Gly-His-Lys acetateTripeptide -
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Biotinoyl tripeptide-1Peptide -
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Acetyl tetrapeptide-5ACE-1 Inhibitor -
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Dipeptide 2ACE Inhibitor -
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Pentapeptide-3Acetylcholine Receptor Antagonist -
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Acetyl tetrapeptide-2Anti-aging Peptide -
HY-118060R
Dipeptide 2 (Standard)Anti-aging Peptide
Actividad biológica
Descripciòn
In Vitro
Acetyl hexapeptide-1 acts directly on melanocytes in hair follicles to promote hair repigmentation. In skin care products, it is used to induce healthy skin pigmentation, helping to improve uneven skin tone and local paleness. Acetyl hexapeptide-1 also reduces skin erythema and inflammatory responses, and helps repair UV-induced DNA damage, making the skin appear healthier[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 448944-47-6
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Appearance Solid
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Peso molecular 870.01
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Fòrmula C43H59N13O7
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Color White to off-white
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Synonyms
Melitane
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Sequence
Ac-{Nle}-Ala-His-{d-Phe}-Arg-Trp-NH2
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Sequence Shortening
Ac-{Nle}-AH-{d-Phe}-RW-NH2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
In Vitro:
H2O : 25 mg/mL (28.74 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.1494 mL | 5.7471 mL | 11.4941 mL | 28.7353 mL |
| 5 mM | 0.2299 mL | 1.1494 mL | 2.2988 mL | 5.7471 mL | |
| 10 mM | 0.1149 mL | 0.5747 mL | 1.1494 mL | 2.8735 mL | |
| 15 mM | 0.0766 mL | 0.3831 mL | 0.7663 mL | 1.9157 mL | |
| 20 mM | 0.0575 mL | 0.2874 mL | 0.5747 mL | 1.4368 mL | |
| 25 mM | 0.0460 mL | 0.2299 mL | 0.4598 mL | 1.1494 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Acetyl hexapeptide-1 Related Classifications
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