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Cat. No.: HY-163662

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AE027

AE027 is a potent inhibitor against both WT and resistant mutation F348Y AChE with the IC₅₀ values of 10 and 43 μM, respectively.

For research use only. We do not sell to patients.

CAS No.: 1011351-65-7
Formula: C₁₈H₂₃ClN₂O₃
Molecular Weight:350.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

AE027 Chemical Structure

CAS No.: 1011351-65-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AE027 is a potent inhibitor against both WT and resistant mutation F348Y AChE with the IC₅₀ values of 10 and 43 μM, respectively^[1].

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 1011351-65-7
Molecular Weight 350.84
Formula C₁₈H₂₃ClN₂O₃
SMILES

ClC1=CC(OCO2)=C2C=C1CN(CC3=CC=CO3)CCCN(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Qin J, et al. Identification of a Novel Inhibitor of Cimex lectularius Acetylcholinesterase. J Agric Food Chem. 2024;72(22):12498-12507. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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AE027

All Cholinesterase (ChE) Isoforms