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Cat. No.: HY-12176S2

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Aliskiren-d₆-1 hemifumarate

Name: Aliskiren-d6-1 hemifumarate
Brand: MedChemExpress
SKU: HY-12176S2
Availability: PreOrder

(Synonyms: CGP 60536-d₆ hemifumarate; CGP60536B-d₆ hemifumarate; SPP 100-d₆ hemifumarate)

Aliskiren-d₆-1 hemifumarate (CGP 60536-d₆-1 hemifumarate) is the deuterium labeled Aliskiren hemifumarate (HY-12177). Aliskiren is an orally active, highly potent and selective renin inhibitor, with IC₅₀ of 1.5 nM. Aliskiren can be used for the research of hypertension, cardiovascular diseases and cancer cachexia.

For research use only. We do not sell to patients.

Formula: C₃₄H₅₁D₆N₃O₁₀
Molecular Weight:673.87

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Aliskiren-d₆-1 hemifumarate Chemical Structure

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Biological Activity
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Chemical Information
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Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 173334-57-1
Molecular Weight 673.87
Formula C₃₄H₅₁D₆N₃O₁₀
SMILES

CC(C)[C@@H](CC1=CC=C(OC)C(OCCCOC)=C1)C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(NCC(C([2H])([2H])[2H])(C(N)=O)C([2H])([2H])[2H])=O.O=C(O)/C=C/C(O)=O.[1/2]
Synonyms

CGP 60536-d₆ hemifumarate; CGP60536B-d₆ hemifumarate; SPP 100-d₆ hemifumarate
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.