Amastatin
Based on 1 publication(s) in Google Scholar
Amastatin is A slow, tightly bound, competitive inhibitor of aminopeptidase (AP) with an IC50 of 0.54 μg/mL for AP-A.
For research use only. We do not sell to patients.
- CAS No.: 67655-94-1
- Formula: C21H38N4O8
- Molecular Weight:474.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
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- Purity & Documentation
- References
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Help & FAQs
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HY-B0134
BestatinAminopeptidase N/Leukotriene A4 Hydrolase Inhibitor -
HY-B0134A
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HY-115194
Amastatin hydrochlorideAminopeptidase Inhibitor -
HY-B0134R
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HY-13731
PPI-2458MetAP-2 Inhibitor -
HY-B0134AR
Bestatin hydrochloride (Standard)Aminopeptidase N/Leukotriene A4 Hydrolase Inhibitor -
HY-B0134B
Bestatin trifluoroacetateAminopeptidase N/Leukotriene A4 Hydrolase Inhibitor -
HY-169596
Arphamenine AAminopeptidase B Inhibitor
Publications Citing Use of MedChemExpress (MCE) Amastatin
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Biological Activity
Description
Chemical Information
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CAS No. 67655-94-1
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Molecular Weight 474.55
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Formula C21H38N4O8
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SMILES
O=C(C[C@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](CC(C)C)N)O)=O)C(C)C)=O)C(C)C)=O)C(O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Aoyagi T, et al. Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes. J Antibiot (Tokyo). 1978 Jun;31(6):636-8. [Content Brief]
[2]. Wilkes SH, et al. The slow, tight binding of bestatin and amastatin to aminopeptidases. J Biol Chem. 1985 Oct 25;260(24):13154-62. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Amastatin Related Classifications
HY-129298 Related Classifications
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