2. Anti-infection
  3. Influenza Virus
  4. Anti-Influenza agent 6

Anti-Influenza agent 6 (compound 19b) shows inhibitory activity against A/WSN/33/H1N1 (EC50 = 0.015 μM) and influenza B virus Yamagata/16/88 (EC50 = 0.073 μM) and Victotis/2/87 (EC50 = 0.067 μM).

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Anti-Influenza agent 6

Anti-Influenza agent 6 Chemical Structure

CAS No. : 2917502-08-8

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Anti-Influenza agent 6 Related Antibodies

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Description

Anti-Influenza agent 6 (compound 19b) shows inhibitory activity against A/WSN/33/H1N1 (EC50 = 0.015 μM) and influenza B virus Yamagata/16/88 (EC50 = 0.073 μM) and Victotis/2/87 (EC50 = 0.067 μM)[1].

Cellular Effect
Cell Line Type Value Description References
HEK-293T CC50
> 100 μM
Compound: 19b
Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
Cytotoxicity against human HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
HEK-293T EC50
0.015 μM
Compound: 19b
Anti-influenza activity against Influenza A virus A/WSN/33(H1N1) infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
Anti-influenza activity against Influenza A virus A/WSN/33(H1N1) infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
HEK-293T EC50
0.036 μM
Compound: 19b
Anti-influenza activity against Influenza A virus H3N2 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
Anti-influenza activity against Influenza A virus H3N2 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
HEK-293T EC50
0.067 μM
Compound: 19b
Anti-influenza activity against Influenza B virus Victoria/2/87 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
Anti-influenza activity against Influenza B virus Victoria/2/87 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
HEK-293T EC50
0.073 μM
Compound: 19b
Anti-influenza activity against Influenza B virus Yamagata/16/88 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
Anti-influenza activity against Influenza B virus Yamagata/16/88 infected in HEK293T cells assessed as reduction in virus-induced cytopathic effect incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
MDCK CC50
> 200 μM
Compound: 19b
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
[PMID: 38775356]
Molecular Weight

797.06

Formula

C42H64N6O7S
CAS No.
SMILES

CC(C)(C)OC(N[C@@H](CCCCNC(OC(C)(C)C)=O)C(NCCCCCCCC(NC(C=C1)=CC=C1NC(NC(C2=CC=C(C=C2)C(C)(C)C)=O)=S)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Anti-Influenza agent 6 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Influenza agent 62917502-08-8Influenza Virusinfluenza B virus Yamagata/16/88Victotis/2/87Inhibitorinhibitorinhibit

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