Anti-Trypanosoma cruzi agent-9
Anti-Trypanosoma cruzi agent-9 is a topoisomerase II inhibitor. Anti-Trypanosoma cruzi agent-9 inhibits the growth of Trypanosoma cruzi and Leishmania donovani.
For research use only. We do not sell to patients.
- CAS No.: 3094993-05-9
- Formula: C19H19N7O
- Molecular Weight:361.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
Topoisomerase II |
In Vitro
Anti-Trypanosoma cruzi agent-9 (Compound example 28) potently inhibits the growth of Trypanosoma cruzi (EC50 <0.1 μM), and Leishmania donovani (EC50 = 0.1-1 μM)[1].
Anti-Trypanosoma cruzi agent-9 does not exhibit significant cytotoxicity to NIH 3T3 fibroblast cells, with a CC50 >10 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3094993-05-9
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Molecular Weight 361.40
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Formula C19H19N7O
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SMILES
CC1=NC(C=CC(N2CC[C@@H](NC(CN3C=NC(C#N)=N3)=O)C2)=C4)=C4C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)