ABAT Antibody (YA7678)
(Synonyms: GABAT, ABAT, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, Gamma-amino-N-butyrate transaminase, L-AIBAT, GABA-AT, GABA transaminase, GABA-T)
Based on 1 Customer Validation
ABAT Antibody (YA7678) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ABAT.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IP, IF-Tissue
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IP
IP: Immunoprecipitation
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:20-50 | 1:100-500 |
Product Details
ABAT Antibody (YA7678) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ABAT.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman, Mouse, Rat Predicted Reactivity: Human
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 56 kDa
A synthesized peptide derived from human ABAT: 20-80/500.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ABAT catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine[1][2].
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Subcellular Localization
Mitochondrion matrix
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Expression
Tissue_Specificity: Liver > pancreas > brain > kidney > heart > placenta -
Isoforms & Post-Translational Modification
P80404: 500 amino acids, molecular weight 56439 Da.
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Subunit
Homodimer; disulfide-linked
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SwissProt ID
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Synonyms
GABAT, ABAT, (S)-3-amino-2-methylpropionate transaminase, GABA aminotransferase, Gamma-amino-N-butyrate transaminase, L-AIBAT, GABA-AT, GABA transaminase, GABA-T
Documentation
References
[1]. Medina-Kauwe LK, et al. 4-Aminobutyrate aminotransferase (GABA-transaminase) deficiency. J Inherit Metab Dis. 1999 Jun;22(4):414-27. [Content Brief]
[2]. Yoon CS, et al. Cysteine-321 of human brain GABA transaminase is involved in intersubunit cross-linking. Mol Cells. 2004 Oct 31;18(2):214-9. [Content Brief]
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