Acetyl-Histone H1oo (Lys163) Antibody
(Synonyms: H1FOO, H1OO, OSH1, H1-8, Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1)Acetyl-Histone H1oo (Lys163) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Acetyl-Histone H1oo (Lys163).
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
Acetyl-Histone H1oo (Lys163) Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Acetyl-Histone H1oo (Lys163).
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 42 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 35 kDa
Synthetic acetylated peptide corresponding to residues surrounding K163 of human Histone H1oo protein.
Endogenous
affinity purified.
Non-conjugated
Acetylated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Acetyl-Histone H1oo may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity)
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Subcellular Localization
Cytoplasm; Nucleus; Chromosome
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Expression
Tissue_Specificity: Oocyte-specific. -
Isoforms & Post-Translational Modification
Acetyl-Histone H1oo has 2 isoforms, Q8IZA3-1: amino acid length is 346, molecular weight is 35813 Da (predicted); Q8IZA3-2: amino acid length is 207, molecular weight is 21010 Da (predicted).
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SwissProt ID
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Synonyms
H1FOO, H1OO, OSH1, H1-8, Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1
Documentation
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