AF488-conjugated HLA-DR Antibody (L243)
(Synonyms: HLA-DR,HLA-DR-AF488,L243)AF488-conjugated HLA-DR Antibody (L243) is a Mouse-derived and AF488 conjugated monoclonal antibody, targeting to HLA-DR.
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Host:
Mouse
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Isotype:
Mouse IgG2a,κ
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Application:
FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Conjugation:
AF488
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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|---|---|
| Dilution Ratio | 5 ul per 106 cells in a 100 µl suspension |
Product Details
AF488-conjugated HLA-DR Antibody (L243) is a Mouse-derived and AF488 conjugated monoclonal antibody, targeting to HLA-DR.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
AF488
Unmodified
Mouse IgG2a,κ
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.2) containing 0.1% Proclin300 and protein stabilizer.
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Storage & Stability
Stored at 2-8°C for 1 year, protect from light, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
HLA-DR is a heterodimeric transmembrane glycoprotein composed of two non-covalently linked chains: an α chain and a β chain. HLA-DR is primarily expressed on the surface of professional antigen-presenting cells (APCs). It functions in antigen presentation and coordinates T-cell activation and differentiation, thereby facilitating the generation of an effective immune response.
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Expression
Tissue_specificity:Expressed in professional APCs: macrophages, dendritic cells and B cells (at protein level). Expressed in thymic epithelial cells (at protein level)
Induction:Up-regulated in dendritic cells upon maturation -
Subunit
Heterotrimer that consists of an alpha chain HLA-DRA, a beta chain HLA-DRB and a peptide (peptide-MHCII)
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Synonyms
HLA-DR,HLA-DR-AF488,L243
Documentation
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