AZIN1 Antibody (YA8387)(PBS only)

Cat. No.: HY-P88703A: Data Sheet User Guide for Antibodies
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AZIN1 Antibody (YA8387) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to AZIN1.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

AZIN1 Antibody (YA8387) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to AZIN1.

Host

Mouse

분자량

Predicted band size: 49.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O14977

Immunogen

Human recombinant protein fragment corresponding to amino acids 260-448 of human AZIN1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000-2500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240)

Subcellular Localization：Nucleus

Expression：
Tissue_Specificity: Expressed in liver

Isoforms & Post-Translational Modification：O14977: 448 amino acids, molecular weight 49535 Da.

Subunit：Monomer (PubMed:26305948)

Synonyms

AZI; AZIA1; OAZI; OAZIN; ODC1L

각종 서류

User Guide for Antibodies (1077 KB)