CCDC93 Antibody (YA8685)

Cat. No.: HY-P89001: Data Sheet User Guide for Antibodies
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CCDC93 Antibody (YA8685) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC93.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CCDC93 Antibody (YA8685) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC93.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 73 kDa

Species Reactivity

Human, Dog, Monkey, Mouse, Rat

SwissProt ID

Q567U6

Immunogen

Human recombinant protein fragment corresponding to amino acids 293-631 of human CCDC93 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129). Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels (PubMed:37172566, PubMed:38459129). The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:25355947, PubMed:28892079). Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947)|(Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface

Subcellular Localization：Early endosome

Isoforms & Post-Translational Modification：Q567U6: 631 amino acids, molecular weight 73198 Da.

Subunit：Component of the commander complex consisting of the CCC subcomplex and the retriever subcomplex (PubMed:37172566, PubMed:38459129, PubMed:25355947, PubMed:28892079)

Synonyms

FLJ10996; FLJ25197; MGC13033

Documentation

User Guide for Antibodies (1077 KB)