CD30 Antibody (YA1390)
(Synonyms: CD30; D1S166E; KI1; Tnfrsf8)CD30 Antibody (YA1390) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD30.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
CD30 Antibody (YA1390) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD30.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 120 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 64 kDa
A synthesized peptide derived from human CD30 aa570-595/595.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD30 receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B[1][2].
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Cytoplasm
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Expression
Tissue_specificity:Protein levels were detected in alveolar macrophages. -
Isoforms & Post-Translational Modification
P28908 has 3 isomers: P28908-1: 63747 Da (predicted); P28908-2: 14088 Da (predicted); P28908-3: 50935 Da (predicted).
Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832) -
Subunit
Interacts with TRAF1, TRAF2, TRAF3 and TRAF5
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SwissProt ID
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Synonyms
CD30; D1S166E; KI1; Tnfrsf8
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Research Field
Immunology
Documentation