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Cat. No.: HY-P87567

CDC16 Antibody (YA7251)

CDC16 Antibody (YA7251) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC16.

For research use only. We do not sell to patients.

Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	FC FC: Flow Cytometry	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence
Dilution Ratio	1:500-2000	1:50-100	1:50-200

Description

CDC16 Antibody (YA7251) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC16.

Host Rabbit
Clonality Recombinant,Monoclonal
Species Reactivity
Human, Mouse Predicted Reactivity: Rat

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
Observed Molecular Weight

Observed band size: 72 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 72 kDa

Immunogen

A synthesized peptide derived from human CDC16

Sensitivity

Endogenous

Purification

affinity purified by Protein A

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Appearance

Liquid
Formulation

Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CDC16 component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The APC/C complex catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins^[1]^[2].
Subcellular Localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Cytoplasm, cytoskeleton, spindle
Isoforms & Post-Translational Modification

Q13042 has four isomers: Q13042-1: 71656 Da (predicted); Q13042-2: 71527 Da (predicted); Q13042-3: 65860 Da (predicted); Q13042-4: 60371 Da (predicted).
Phosphorylated
Subunit

V-shaped homodimer
SwissProt ID

Q13042