CDKN3 Antibody (YA7933)
(Synonyms: CDI1; CIP2; KAP; KAP1)CDKN3 Antibody (YA7933) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDKN3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 | 1:100 |
Product Details
CDKN3 Antibody (YA7933) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CDKN3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 23.6 kDa
Full length human recombinant protein of human CDKN3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDKN3 may play a role in cell cycle regulation. Dual specificity CC phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner[1][2][3].
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Subcellular Localization
Cytoplasm, perinuclear region
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Expression
Induction: Up-regulated in breast and prostate cancer cells
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Isoforms & Post-Translational Modification
Q16667 has two isomers: Q16667-1: 23805 Da (predicted); Q16667-2: 19359 Da (predicted).
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Subunit
Interacts with cyclin-dependent kinases such as CDK1, CDK2 and CDK3
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SwissProt ID
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Synonyms
CDI1; CIP2; KAP; KAP1
Documentation
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