2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. CHD1 Antibody (YA7042)

CHD1 Antibody (YA7042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CHD1.

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容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

CHD1 Antibody (YA7042) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CHD1.
Host

Mouse
Clonality

Monoclonal
分子量
Predicted band size: 197 kDa;
Observed band size: 260 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Immunogen

Recombinant protein within Human CHD1 aa 1,479-1,710 / 1,710.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100
Sensitivity Endogenous 純度 Protein A affinity purified.
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3 (PubMed:18042460, PubMed:28866611). Required for maintaining open chromatin and pluripotency in embryonic stem cells (By similarity)
Subcellular Localization：Nucleus,Cytoplasm
Expression：
Tissue_Specificity: Expressed in many tissues including in the brain, where the highest level of expression is found in the cerebellum and basal ganglia
Isoforms & Post-Translational Modification：O14646 has two isomers: O14646-1: 196688 Da (predicted); O14646-2: 196590 Da (predicted).
Subunit：Component of the SAGA complex (By similarity)
Synonyms
ATP dependent helicase CHD 1 antibody; ATP-dependent helicase CHD1 antibody; CHD 1 antibody; CHD-1 antibody; Chd1 antibody; CHD1_HUMAN antibody; Chromodomain helicase DNA binding protein 1 antibody; Chromodomain-helicase-DNA-binding protein 1 antibody; DKFZp686E2337 antibody; OTTHUMP00000222625 antibody
ドキュメンテーション
User Guide for Antibodies (1077 KB)

CHD1 Antibody (YA7042) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
CHD1 Antibody (YA7042)
製品番号:
HY-P87359
数量:
MCE 日本正規代理店:

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